2-Amino-5-chlorophenol Chemical Properties

Melting point:

145-153 °C (lit.)

Boiling point:

185.5°C (rough estimate)

Density 

1.2028 (rough estimate)

vapor pressure 

0.002-0.094Pa at 20-50℃

refractive index 

1.5618 (estimate)

solubility 

soluble in Methanol

pka

8.79±0.10(Predicted)

form 

Powder

color 

Light brown

CAS DataBase Reference

28443-50-7(CAS DataBase Reference)

EPA Substance Registry System

Phenol, 2-amino-5-chloro- (28443-50-7)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-36/37/39

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

HS Code 

29222990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-Amino-5-chlorophenol Usage And Synthesis

Chemical Properties

light brown fine crystalline powder

Uses

2-Amino-5-chlorophenol may be used to synthesize 2-amino-5-chloromuconic semialdehyde and benzoxazole derivatives.

Definition

ChEBI: Phenol carrying amino and chloro substituents at positions 2 and 5 respectively. It is part of the degradation pathway of 4-chloronitrobenzene, CHEBI:34399.

General Description

2-Amino-5-chlorophenol can be synthesized from 2-chloro-5-nitrophenol via reduction. It can also be obtained from 1-chloro-4-nitrobenzene by using a bacterial strain LW1. 2-Amino-5-chlorophenol participates in the condensation reaction with acetylferrocene to afford ferrocenyl Schiff bases bearing a phenol group.

2-Amino-5-chlorophenol(28443-50-7)Related Product Information

• Betaine
• 2-Aminophenol
• Baclofen
• ALTRENOGEST
• 2-Amino-5-chlorobenzoic acid
• Epichlorohydrin
• 4-Aminophenol
• Glycine
• 3-Aminophenol
• Hexachlorophene
• Acetaminophen
• 3-Chlorophenol
• 2-Amino-5-chlorobenzonitrile
• 4-Chlorophenol
• Bithionol
• Chloroacetic acid
• Pentachlorophenol
• Difluorochloromethane