3-(3-(Trifluoromethyl)phenyl)propanal Chemical Properties

Boiling point:

207.4±35.0 °C(Predicted)

Density 

1.192±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

Soluble in Chloroform, Dichloromethane, Ethyl acetate

form 

Oil

color 

Clear colorless to pale yellow oily liquid

Stability:

Not very stable, new spot on TLC if kept at r.t. o/n.

InChI

InChI=1S/C10H9F3O/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1,3,5-7H,2,4H2

InChIKey

APCCHYPQHODSBD-UHFFFAOYSA-N

SMILES

C1(CCC=O)=CC=CC(C(F)(F)F)=C1

Safety Information

HS Code 

2912490090

3-(3-(Trifluoromethyl)phenyl)propanal Usage And Synthesis

Uses

3-(Trifluoromethyl)benzenepropanal is a compound useful in organic synthesis.

Chemical Properties

Colourless Oil

Uses

3-(Trifluoromethyl)benzenepropanal (cas# 21172-41-8) is a compound useful in organic synthesis.

Synthesis

A solution of 3-(Trifluoromethyl) benzene propanol (1.0 g, 4.90 mmol) in dichloromethane (20 ml) is cooled in a water/ice bath, treated in succession with DMSO (770 mg, 9.80 mmol) and P2O5 (1.39 g, 9.80 mmol) and left under stirring for 30 minutes, while temperature raises to 20°C. The reaction mixture is then cooled in water/ice bath and triethylamine (2.4 ml, 17.15 mmol). The resulting solution is kept under stirring while the temperature raises to 20°C. After one hour, the mixture is treated with 5 per cent HCl, the phases are separated, and the organic one is further washed with 5 per cent HCl. The organic phase is then washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure to afford 0.99 g of the aldehyde of 3-(3-(Trifluoromethyl)phenyl)propanal in quantitative yield.

3-(3-(Trifluoromethyl)phenyl)propanal(21172-41-8)Related Product Information

• (R)-(+)-1-(1-Naphthyl)ethylamine
• 3-(3'-TRIFLUOROMETHYL PHENYL) PROPANOL
• 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID
• 1-NAPHTHALEN-2-YL-ETHYLAMINE
• 3-(Trifluoromethyl)benzaldehyde
• Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester
• 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride
• 3-(3-METHYLPHENYL)PROPIONIC ACID
• 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)-
• (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
• (S)-(-)-1-(1-Naphthyl)ethylamine
• 1-(1-NAPHTHYL)ETHANOL
• 3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid
• 3-(Trifluoromethyl)styrene
• 3-(Trifluoromethyl)cinnamic acid
• 3-(3-METHYLPHENYL)PROPIONALDEHYDE
• Benzene, 1-(3-chloropropyl)-3-(trifluoroMethyl)-
• (E)-m-(trifluoromethyl)cinnamic acid