4-Fluorophenylacetonitrile Chemical Properties

Melting point:

86°C

Boiling point:

119-120 °C/18 mmHg (lit.)

Density 

1.126 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5002(lit.)

Flash point:

227 °F

storage temp. 

Inert atmosphere,Room Temperature

form 

Liquid

color 

Clear colorless to light yellow

BRN 

1907764

Exposure limits

NIOSH: IDLH 25 mg/m3

InChIKey

JHQBLYITVCBGTO-UHFFFAOYSA-N

CAS DataBase Reference

459-22-3(CAS DataBase Reference)

NIST Chemistry Reference

4-Fluorophenylacetic acid nitrile(459-22-3)

EPA Substance Registry System

Benzeneacetonitrile, 4-fluoro- (459-22-3)

Safety Information

Hazard Codes 

Xn,T,Xi

Risk Statements 

20/21/22-36/37/38-20/21/22/36/37/38-20/20/22

Safety Statements 

26-36-24/25-26/36/37/39

RIDADR 

UN 3276 6.1/PG 3

WGK Germany 

3

RTECS 

AM0210000

Hazard Note 

Toxic

TSCA 

T

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269090

MSDS

• Language:English Provider:4-Fluorophenylacetonitrile
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4-Fluorophenylacetonitrile Usage And Synthesis

Chemical Properties

Clear light yellow liquid

Uses

4-Fluorophenylacetonitrile is used as a reagent in the synthesis of novel Daidzein analogs which exhibit anti-influenza activity in vitro. It is also used as a reagent in the synthesis of benzylbenzo[d]thiazole sulfonamides which exhibit anti-inflammatory activity.

General Description

4-Fluorophenylacetonitrile is starting reagent in the synthesis of 1-Alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives.

Biochem/physiol Actions

4-Fluorophenylacetonitrile undergoes biotransformation to 4-Fluorophenylacetic acid by marine fungi, Aspergillus sydowii Ce19.

4-Fluorophenylacetonitrile(459-22-3)Related Product Information

• 4-Fluorobenzaldehyde
• Cyhalothrin
• FLUCYTHRINATE
• Florfenicol
• Cyhalothrin
• 4-Fluorobenzoic acid
• 4-Fluorobenzyl chloride
• 4-Fluoroanisole
• 4-Fluorophenylacetic acid
• Transfluthrin
• 4'-Fluoropropiophenone
• p-Nitrophenylacetonitrile
• Copper(I) Cyanide
• Iminodiacetonitrile
• 4-Fluorophenethylamine
• 4-Chlorobenzyl cyanide
• 4-Fluorobenzonitrile
• 2-(Chloromethyl)benzonitrile