2-Bromo-5-fluorobenzotrifluoride Chemical Properties

Boiling point:

136-143 °C(lit.)

Density 

1.695 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.465(lit.)

Flash point:

147 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

color 

Colorless to Light orange to Yellow

BRN 

2643544

CAS DataBase Reference

40161-55-5(CAS DataBase Reference)

NIST Chemistry Reference

2-Bromo-5-fluorobenzotrifluoride(40161-55-5)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36/37/39-37-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29039990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Bromo-5-fluorobenzotrifluoride Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

2-Bromo-5-fluorobenzotrifluoride is an organofluorobenzene compound mainly used as an organic reagent and pharmaceutical intermediate, and can be used as a starting material for the preparation of HSD-016.  HSD-016 inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD1) to convert cortisone into cortisol for the development of drugs for the treatment of type 2 diabetes.

2-Bromo-5-fluorobenzotrifluoride(40161-55-5)Related Product Information

• 3-Fluorobenzotrifluoride
• 1,4-Bis(trifluoromethyl)-benzene
• Xylene
• 2-Methylbenzotrifluoride
• 4-Fluorobenzotrifluoride
• 2-Fluorobenzotrifluoride
• Benzene
• 4-Bromotoluene
• 3-Bromo-5-fluorobenzotrifluoride
• Ethyl bromodifluoroacetate
• 2-Bromo-5-fluorotoluene
• Bromobenzene
• Benzotrifluoride
• Tosufloxacin tosylate
• Bromine
• 4-BROMO-2-FLUOROBENZOTRIFLUORIDE
• 5-Amino-4-bromo-2-fluorobenzotrifluoride, 97%
• Fluorine