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2-Biphenylcarboxaldehyde

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2-Biphenylcarboxaldehyde Basic information

Product Name:
2-Biphenylcarboxaldehyde
Synonyms:
  • (1,1’-biphenyl)-2-carboxaldehyde
  • 2-difenilaldeide
  • BIPHENYL-2-CARBALDEHYDE
  • BIPHENYL-2-CARBOXALDEHYDE
  • 2-PHENYLBENZALDEHYDE
  • 2-BIPHENYLCARBOXALDEHYDE
  • 2-FORMYL-BIPHENYL
  • Biphenyl-2-carboxaldehyde 96%
CAS:
1203-68-5
MF:
C13H10O
MW:
182.22
Product Categories:
  • Biphenyls
  • Aldehydes
  • C10 to C21
  • Carbonyl Compounds
Mol File:
1203-68-5.mol
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2-Biphenylcarboxaldehyde Chemical Properties

Melting point:
202 °C
Boiling point:
91-92 °C/0.15 mmHg (lit.)
Density 
1.130 g/mL at 25 °C (lit.)
refractive index 
n20/D >1.6220(lit.)
Flash point:
215 °F
storage temp. 
2-8°C
solubility 
Chloroform, Ethyl Acetate
form 
Clear Liquid
CAS DataBase Reference
1203-68-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
DV1771000
HS Code 
29122990
Toxicity
mouse,LD50,unreported,> 1500mg/kg (1500mg/kg),Farmaco, Edizione Scientifica. Vol. 19, Pg. 964, 1964.

MSDS

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2-Biphenylcarboxaldehyde Usage And Synthesis

Chemical Properties

2-Biphenylcarboxaldehyde is Clear Liquid

Uses

2-Biphenylcarboxaldehyde is a reactant used in the preparation of imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Biphenylcarboxaldehyde is also used in the p reparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin.

Uses

Biphenyl-2-carboxaldehyde may be used in the preparation of 9-ethylthiofluorene.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 1523, 1989 DOI: 10.1021/jo00268a009

General Description

Biphenyl-2-carboxaldehyde is an oxygen-containing polycyclic aromatic hydrocarbon derivative (OPAH). It can be prepared via Suzuki cross-coupling reaction between phenyl boronic acid and 2-bromobenzaldehyde.

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