TRIMETHYL-BETA-CYCLODEXTRIN Chemical Properties

Melting point:

170-178 °C(lit.)

refractive index 

160 ° (C=1, CHCl3)

storage temp. 

2-8°C

solubility 

H₂O: 50 mg/mL, slightly turbid, colorless

form 

Solid powder or crystals

color 

White to off-white

optical activity

[α]25/D +157±4°, c = 1% in H2O

BRN 

78748

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

29400090

MSDS

• Language:English Provider:SigmaAldrich

TRIMETHYL-BETA-CYCLODEXTRIN Usage And Synthesis

Uses

Trimethyl-β-cyclodextrin (CAS# 55216-11-0) is β-cyclodextrin (C987830) derivative used to solubilize steroids in aqueous solution to increase their bioavailability.

Uses

Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:

• To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.
• To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC).
• In the determination of analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).

General Description

Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a β-cyclodextrin derivative that finds potential use in pharmaceutical, food and cosmetic applications. Its attractive features include: the non-polar cavity desirable for its use as a molecular host for a wide range of molecules and its affinity for organic compounds in solution as well as crystalline phases.

TRIMETHYL-BETA-CYCLODEXTRIN(55216-11-0)Related Product Information

• 2-Hydroxypropyl-β-cyclodextrin
• beta-Cyclodextrin methyl ethers
• Betadex Sulfobutyl Ether Sodium
• 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN
• α-Cyclodextrine
• β-Cyclodextrin
• TRIMETHYL-BETA-CYCLODEXTRIN
• TRIACETYL-BETA-CYCLODEXTRIN
• HEPTAKIS-(2 3 6-TRI-O-ETHYL)-BETA-
• HEPTAKIS(2,3,6-TRI-O-''OCTYL)-BETA-CYCLODEXTRIN
• HEPTAKIS-(3-O-BUTYRYL-2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN
• HEPTAKIS(3-O-ACETYL-2 6-DI-O-METHYL)-
• 3-O-TRIFLUOROACETYLPERMETHYL-BETA-CYCLODEXTRINE
• HEPTAKIS(2,6-DI-O-METHYL-3-O-''PENTYL)-BETA-CYCLODEXTRIN*
• HEPTAKIS(3-O-ALLYL-2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN
• HEPTAKIS-(3-O-TRIFLUOROACETYL-2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN
• Heptakis-(2,6-di-O-butyl-3-O-acetyl)-beta-Cyclodextrin
• Heptakis-(2,6-di-O-pentyl-3-O-acetyl)-beta-Cyclodextrin