Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Catalyst and Auxiliary >  Polyethylene glycol derivatives >  Methoxypolyethylene glycol amine

Methoxypolyethylene glycol amine

Basic information Safety Supplier Related

Methoxypolyethylene glycol amine Basic information

Product Name:
Methoxypolyethylene glycol amine
Synonyms:
  • AMINOPOLYETHYLENE GLYCOL 10,000 MONOMETHYL ETHER
  • AMINOPOLYETHYLENE GLYCOL 10'000 MONOMETHYL ETHER
  • AMINOPOLYETHYLENE GLYCOL 20,000 MONOMETHYL ETHER
  • Poly(ethylene glycol) α-2-aMinoethyl, ω-Methoxy
  • MPEGn-NH2 2K, 5K, 10K, 20K
  • MPEG-AMine, average M.W. 4,000
  • MPEG-AMine, average M.W. 10,000
  • MPEG-AMine, average M.W. 1,000
CAS:
80506-64-5
MF:
C5H13NO2
MW:
119.16222
Product Categories:
  • Polydispersed PEG
  • PEG
  • Amine
  • Materials Science
  • Monofunctional PEGs
  • Poly(ethylene glycol) and Poly(ethylene oxide)
  • Polymer Science
  • Polymers
Mol File:
80506-64-5.mol
More
Less

Methoxypolyethylene glycol amine Chemical Properties

Melting point:
58-61 °C(lit.)
Flash point:
>110℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), MEtanol (Slightly)
form 
Granular Solid
color 
White to off-white
Water Solubility 
Soluble in water.
EPA Substance Registry System
Poly(oxy-1,2-ethanediyl), .alpha.-(2-aminoethyl)-.omega.-methoxy- (80506-64-5)
More
Less

Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
2-9
TSCA 
Yes
HS Code 
39072090

MSDS

More
Less

Methoxypolyethylene glycol amine Usage And Synthesis

Description

m-PEG15-amine is a PEG linker containing an amino group and 15 PEG units. It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

PEG functionalized with amine for ligation and coupling reactions.

Uses

MPEG-NH2 is a reactant in synthesis of pH-sensitive polymeric micelles for intracellular drug delivery.

Uses

Methoxypolyethylene glycol amine is generally used for the chemical modification of biologically active compounds and therapeutic agents. It has been used to increase the aqueous solubility of long-wavelength voltage-sensitive dyes and to prepare the PEG-coated fluorescent beads in studying large-scale rotational cytoplasmic flow.

Application

Methoxypolyethylene glycol amine is used in the reduction of immunogenicity and increasing serum half life.Methoxypolyethylene glycol amine can:
Form dendritic micelles to enhance the solubility of hydrophobic compounds.
Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
PEG functionalized with amine for ligation and coupling reactions.

Methoxypolyethylene glycol amineSupplier

NBC (Shanghai) Chemical Co.,Ltd Gold
Tel
13671558889
Email
market@nbcchem.com
Zhengzhou Convergence Chemical Co. LTD Gold
Tel
0371-53736046 13393710386
Email
2853979814@qq.com
Xinyanpomei Gold
Tel
15850660754
Email
15850660754@163.com
TIANJING WELCOME SCIENCE AND TECHMOLOGY DEVELOPMENT CO,LTD. Gold
Tel
18526832783
Email
18526832783@163.com
Shandong Baostai Medical Materials Co. LTD Gold
Tel
0531-95836715 15550029578
Email
958367155@qq.com