Basic information Safety Supplier Related

PPAHV

Basic information Safety Supplier Related

PPAHV Basic information

Product Name:
PPAHV
Synonyms:
  • PPAHV
  • PHORBOL 12-PHENYLACETATE 13-ACETATE 20-HOMOVANILLATE
  • [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9-[phenylacetyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methylesterbenzeneaceticacid
  • PPAHV >99%
  • ((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5
  • Resiniferatoxin Impurity 3
  • Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9-[(phenylacetyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methyl ester
CAS:
175796-50-6
MF:
C39H44O11
MW:
688.76
Product Categories:
  • Antagonist
Mol File:
175796-50-6.mol
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PPAHV Chemical Properties

Boiling point:
792.4±60.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
solubility 
DMSO: soluble
form 
solid
pka
9.85±0.20(Predicted)
color 
white
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Safety Information

WGK Germany 
3

MSDS

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PPAHV Usage And Synthesis

Uses

PPAHV is non-pungent resiniferatoxin-type phorboid vanilloid and agonist.

Biological Activity

Non-pungent vanilloid TRPV1 (VR1) receptor agonist (K i = 3.1 μ M) that displays non-cooperative binding. Induces apoptosis via a non-VR1 mechanism in Jurkat cells and causes vasoconstriction in vivo .

PPAHVSupplier

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