CONGLOBATIN
CONGLOBATIN Basic information
- Product Name:
- CONGLOBATIN
- Synonyms:
-
- (3E,5R,7S,8S,11E,13R,15S,16S)-3,5,7,11,13,15-Hexamethyl-8,16-bis(5-oxazolylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
- FW-04-806
- CONGLOBATIN
- Conglobatin, >=99%
- 1,9-Dioxacyclohexadeca-3,11-diene-2,10-dione, 3,5,7,11,13,15-hexamethyl-8,16-bis(5-oxazolylmethyl)-, (3E,5R,7S,8S,11E,13R,15S,16S)-
- Conglobactin
- (3E,5R,7S,8S,11E,13R,15S,16S)-3,5,7,11,13,15-hexamethyl-8,16-bis[(1,3-oxazol-5-yl)methyl]-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
- NGLOBATIN
- CAS:
- 72263-05-9
- MF:
- C28H38N2O6
- MW:
- 498.61
- Product Categories:
-
- Antibiotic
- Mol File:
- 72263-05-9.mol
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CONGLOBATIN Chemical Properties
- Density
- 1.060±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- White to off-white solid.
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CONGLOBATIN Usage And Synthesis
Uses
Isolated from Streptomyces conglobatus, conglobatin has a unusual, dimeric, macrolide dilactone structure with pendant oxazole groups. Conglobatin exhibits an IC50 of 0.63 μg/ml in a NFAT-dependant transcription assay. No toxicity was observed at doses up to 1000 mg/kg when administered to mice either orally or interperitoneally.
Uses
Conglobatin is a macrolide dilactone from Streptomyces. It exhibits anticancer and immunosuppressant properties.
CONGLOBATINSupplier
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