3-FLUORO-2-FORMYLPYRIDINE Chemical Properties

Melting point:

49 °C

Boiling point:

112°C/50mmHg(lit.)

Density 

1.269±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

soluble in Methanol

pka

1.25±0.10(Predicted)

form 

Solid

color 

White to Green to Brown

Water Solubility 

Slightly soluble in water.

CAS DataBase Reference

31224-43-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

Hazard Note 

Harmful

HS Code 

2933399990

3-FLUORO-2-FORMYLPYRIDINE Usage And Synthesis

Uses

3-Fluoropyridine-2-carboxaldehyde is used to prepare taxoids derived from 9β-dihydrobaccatin-9,10-acetals with anti-tumor activities. It is also an intermediate used to synthesize S-3578 derivatives with potent activities against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa.

Synthesis Reference(s)

Tetrahedron, 39, p. 2009, 1983 DOI: 10.1016/S0040-4020(01)91919-2

3-FLUORO-2-FORMYLPYRIDINE(31224-43-8)Related Product Information

• 3-FLUORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
• 2-Acetyl-3-fluoropyridine
• 3-Fluoro-6-bromo-2-pyridinecarboxaldehyde
• 6-Chloro-3-fluoro-pyridine-2-carboxylic acid
• 3,5-Difluoropicolinic acid
• 3-FLUOROPYRIDINE-2-CARBOXYLIC ACID
• 3-FLUORO-2-FORMYLPYRIDINE
• 5-BROMO-3-FLUOROPICOLINIC ACID
• 5-FLUORO-2-FORMYLPYRIDINE
• 5-Chloro-2-fluoropyridine-3-carboxaldehyde
• 3-FLUORO-5-FORMYLPYRIDINE
• 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
• 2-FLUORO-5-FORMYLPYRIDINE
• 4-FLUORO-3-FORMYLPYRIDINE
• 2-CHLORO-5-FLUORO-4-FORMYLPYRIDINE
• 2-FLUORO-6-FORMYLPYRIDINE
• 2-FLUORO-4-FORMYLPYRIDINE
• 2-CHLORO-5-FLUORO-3-FORMYLPYRIDINE