Basic information Description References Safety Supplier Related
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Polysorbate 20

Basic information Description References Safety Supplier Related

Polysorbate 20 Basic information

Product Name:
Polysorbate 20
Synonyms:
  • Polisorbate 20- PS 20
  • Tween 20 (Trademark of ICI America, Inc.)
  • Tween 20 
  • Tween 20 1LT
  • Twain 20
  • TWEEN(R) 20 Vetec(TM) reagent grade, 40%
  • Tween 20 Tween 20 1LT
  • Polysorbate 20 9005-64-5
CAS:
9005-64-5
MF:
C26H50O10
MW:
522.6692
EINECS:
500-018-3
Product Categories:
  • -
  • detergent
  • Ester Ether Type (Surfactants)
  • #N/A
  • Functional Materials
  • Nonionic Surfactants
  • Surfactants
  • Biochemistry
  • Nonionic Surfactants (for Biochemistry)
  • Surfactants (for Biochemistry)
  • Alphabetical Listings
  • Flavors and Fragrances
  • O-P
Mol File:
9005-64-5.mol
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Polysorbate 20 Chemical Properties

Boiling point:
100 °C
Density 
1.11 g/mL at 20 °C
vapor pressure 
<1.4 hPa (20 °C)
FEMA 
2915 | POLYSORBATE 20
refractive index 
n20/D 1.468(lit.)
Flash point:
>230 °F
storage temp. 
0-6°C
solubility 
100 g/L
form 
viscous liquid
Specific Gravity
1.090~1.130 (20/20℃)
color 
Amber
PH
6-8 (50g/l, H2O, 20℃)
Water Solubility 
100 g/L
Hydrophilic-Lipophilic Balance (HLB)
16.7
Stability:
Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System
Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.(9005-64-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
22-36/37/38-37/38-41
Safety Statements 
24/25-36/37/39-36-26
WGK Germany 
1
RTECS 
TR7400000
10-23
TSCA 
Yes
HS Code 
34021300
Toxicity
LD50 orally in Rabbit: 38900 mg/kg

MSDS

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Polysorbate 20 Usage And Synthesis

Description

Tween 20, whose common commercial names includes Alkest TW 20 and Polysorbate 20, is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. It is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.
Tween 20 is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry, such as Western blots and ELISAs, helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading. Besides, Tween 20 also has applications in food production as a common food grade additive which are found in many consumables on the market today. It can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry.

References

https://en.wikipedia.org/wiki/Polysorbate_20
http://www.organic-creations.com/thickeners-stabilizers/599-polysorbate-20

Chemical Properties

Polysorbate 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It has a faint, characteristic odor and a warm, somewhat bitter taste.

Chemical Properties

Yellow liquid

Uses

Pharmaceutic aid (surfactant).

Uses

polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water.

Definition

ChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group.

Preparation

By condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization at the free hydroxyl groups.

brand name

Tween 20 (ICI Americas).

Safety Profile

Moderately toxic by intravenous route. Mddly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Polysorbate 20 Preparation Products And Raw materials

Raw materials

Polysorbate 20Supplier

Guangdong Runhua Chemical Co., Ltd. Gold
Tel
020-87568805;13602895725
Email
lyl@gdrunhua.com
Products Intro
Product Name:Polysprbate20;Tween20
CAS:9005-64-5
Purity:98% Package:25KG;220KG
Shanghai Aladdin Bio-Chem Technology Co.,LTD Gold
Tel
021-20337333/400-620-6333
Email
sale@aladdin-e.com
Products Intro
Product Name:Tween 20
CAS:9005-64-5
Purity:CP Package:769RMB/5L
Zhejiang Lianshuo Biotechnology Co., Ltd. Gold
Tel
18616526224
Email
lianshuo@vip.126.com
Products Intro
Product Name:TWEEN 20, 10% SOLUTION, PEROXIDE-FREE
CAS:9005-64-5
Purity:PROTEOMICS GRADE Package:10ML-5PK Remarks:M228
J & K SCIENTIFIC LTD.
Tel
400-666-7788 +86-10-82848833
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro
Product Name:Tween 20
CAS:9005-64-5
Package:1L;250ML;50ML
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
Email
sh@meryer.com
Products Intro
Product Name:Tween 20 (=Polyoxyethylene Sorbitan Monolaurate)
CAS:9005-64-5
Package:25g;500g Remarks:T0543