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(R)-(+)-Tetrahydro-2-furoic acid

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(R)-(+)-Tetrahydro-2-furoic acid Basic information

Product Name:
(R)-(+)-Tetrahydro-2-furoic acid
Synonyms:
  • (R)-(+)-2-Tetrahydrofuroic acid, 99% (98% ee) 1GR
  • (R)-(+)-Tetrahydro-2-furoic acid, 99% (98% ee)
  • (R)-(+)-Tetrahydro-2-furoic acid 99%
  • (2R)-oxolane-2-carboxylic acid
  • (R)-(+)-Tetrahydrofuran-2-carboxylic Acid
  • (R)-(+)-Tetrahydro-2-furoic acid≥ 99% (GC, Chiral purity)
  • (R)-Tetrahydrofuran-2-carboxylic Acid,99%e.e.
  • (R)-2-TETRAHYDROFUROIC ACID
CAS:
87392-05-0
MF:
C5H8O3
MW:
116.12
EINECS:
627-523-2
Product Categories:
  • Furans
  • Carbonic Acid
  • Chiral Compounds
  • Miscellaneous
  • chiral
  • Tetrahydrofuran Series
  • CARBOXYLICACID
  • Carboxylic Acids & Deriv.
  • CHIRAL CHEMICALS
  • Chiral Compound
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
Mol File:
87392-05-0.mol
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(R)-(+)-Tetrahydro-2-furoic acid Chemical Properties

Boiling point:
128-129 °C13 mm Hg(lit.)
alpha 
+19.6±0.2°(neat) (D/20℃)
Density 
1.209 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.46(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
pka
3.60±0.20(Predicted)
color 
Colorless to Light yellow
optical activity
[α]23/D +4°, c = 1 in methanol
BRN 
4658739
InChI
InChI=1S/C5H8O3/c6-5(7)4-2-1-3-8-4/h4H,1-3H2,(H,6,7)/t4-/m1/s1
InChIKey
UJJLJRQIPMGXEZ-SCSAIBSYSA-N
SMILES
O1CCC[C@@H]1C(O)=O
CAS DataBase Reference
87392-05-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
22-34-36/37/38
Safety Statements 
26-36/37/39-45-36
RIDADR 
UN 3265 8/PG 3
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29321900

MSDS

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(R)-(+)-Tetrahydro-2-furoic acid Usage And Synthesis

Description

(R)-(+)-2-Tetrahydrofuroic acid is an important pharmaceutical intermediate compound used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs.

Chemical Properties

Colorless to light yellow liquid

Uses

(R)-(+)-2-Tetrahydrofuroic acid is a heterocyclic derivative and can be used as a pharmaceutical intermediate.

(R)-(+)-Tetrahydro-2-furoic acid Preparation Products And Raw materials

Raw materials

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