Darifenacin 3-Hydroxy Impurity Chemical Properties

Boiling point:

644.1±55.0 °C(Predicted)

Density 

1.247±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO: soluble; Methanol: soluble

form 

A solid

pka

13.52±0.20(Predicted)

Darifenacin 3-Hydroxy Impurity Usage And Synthesis

Description

3-hydroxy Darifenacin is a metabolite of darifenacin . It is an antagonist of M_1-5 muscarinic receptors (K_is = 17.78, 79.43, 2.24, 36.31, and 6.17 nM, respectively, in CHO cells).

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