Benzyl salicylate Chemical Properties

Melting point:

18-20 °C

Boiling point:

168-170 °C5 mm Hg(lit.)

Density 

1.176 g/mL at 25 °C(lit.)

vapor pressure 

0.01Pa at 25℃

refractive index 

n20/D 1.581(lit.)

FEMA 

2151 | BENZYL SALICYLATE

Flash point:

>230 °F

storage temp. 

-20°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

8.11±0.30(Predicted)

form 

Liquid

color 

Thick colorless liquid

Odor

pleasant odor

Odor Type

balsamic

Water Solubility 

Slightly soluble

JECFA Number

904

Merck 

14,1144

BRN 

2115365

Dielectric constant

4.1（20℃）

InChIKey

ZCTQGTTXIYCGGC-UHFFFAOYSA-N

LogP

4

CAS DataBase Reference

118-58-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 2-hydroxy-, phenylmethyl ester(118-58-1)

EPA Substance Registry System

Benzyl salicylate (118-58-1)

Safety Information

Hazard Codes 

Xi,N

Risk Statements 

36/37/38-51/53-43

Safety Statements 

26-36-24/25-61-37-24

WGK Germany 

2

RTECS 

VO1750000

TSCA 

Yes

HS Code 

29182900

Hazardous Substances Data

118-58-1(Hazardous Substances Data)

Toxicity

LD50 orl-rat: 2227 mg/kg FCTXAV 11,1029,73

MSDS

• Language:English Provider:Salicylic acid benzyl ester
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Benzyl salicylate Usage And Synthesis

Description

Benzyl salicylate is a salicylic acid benzyl ester, a chemical compound most frequently used in cosmetics. It appears as an almost colorless liquid with a mild odor described as "very faint, sweetfloral, slightly balsamic" by those who can smell it, but many people either can't smell it at all or describe its smell as "musky". Trace impurities can have a significant influence on the odour.[1] It occurs naturally in a variety of plants and plant extracts and is widely used in blends of fragrance materials.
There is some evidence that people can become sensitized to this material and as a result there is a restriction standard concerning the use of this material in fragrances by the International Fragrance Association.
It is used as a solvent for crystalline synthetic musks and as a component and fixative in floral perfumes such as carnation, jasmine, lilac, and wallflower.

Chemical Properties

Benzyl Salicylate occurs in several essential oils, is a colorless, viscous liquid with a weak, sweet, slightly balsamic odor and a sweet, currant-like taste. It is soluble in ethanol, most non-volatile and volatile oils, slightly soluble in propylene glycol, insoluble in glycerin and practically insoluble in water.

Occurrence

It has been reported in small amounts in carnation oil (Dianthus caryophyllus L.) and in larger amounts in the oil of Primula auricula. Also found in American cranberry, clove bud, peppermint oil and buckwheat.

Uses

Benzyl Salicylate is an chemical compound commonly used in the cosmetic industry. Benzyl Salicylate is also found in essential oils from green tea and was shown to exhibit antioxidant and antimicrobia l activity.

Uses

benzyl salicylate is a fragrance found naturally occurring in carnations and in certain members of the primrose family. Although it can be derived for cosmetic use from natural essential oils, such as jasmine oil, neroli, and ylang-ylang, it can also be synthetically manufactured.

Definition

ChEBI: Benzyl salicylate is a benzoate ester and a member of phenols. It is functionally related to a salicylic acid.

Preparation

By esterification of salicylic acid with benzyl alcohol.

General Description

Colorless liquid. Melting point near room temperature (18-20°C). As fixer in perfumery; in sunscreen preparations.

Air & Water Reactions

Slightly water soluble .

Reactivity Profile

Benzyl salicylate may hydrolyze in aqueous acid or basic solutions. Benzyl salicylate can react with oxidizing materials.

Fire Hazard

Flash point data for Benzyl salicylate are not available, but Benzyl salicylate is probably combustible.

Flammability and Explosibility

Non flammable

Contact allergens

Benzyl salicylate is used as fixer in perfumery and sunscreen preparations. As a (weak) perfume sensitizer, it has to be listed by name in cosmetic preparations in the EU.

Safety Profile

Moderately toxic by ingestion. Seealso BENZYL ALCOHOL, SALICYLIC ACID, andESTERS. Combustible when exposed to heat or flame.When heated to decomposition it emits acrid smoke andirritating fumes. Incompatible with oxidizing materials.

Safety

Benzyl salicylate poses dangers to sensitive skin.  Even in very small amounts, it may cause allergic reactions when applied to the skin. Benzyl salicylate can cause contact dermatitis (skin irritation) to people with sensitive skin types. It is also on the European Commission's list of 26 known allergens. Some of the other ingredients on the fragrance allergen list include linalool, coumarin, geraniol, and limonene.

Benzyl salicylate(118-58-1)Related Product Information

• Benzyl chloroformate
• Benzyl formate
• 4-Nitrobenzyl chloroformate
• Phenyl salicylate
• Benzyl nicotinate
• Benzyl benzoate
• Dimethyl succinate
• Benzyl methacrylate
• Hexyl salicylate
• Salicylic acid
• BUTYL OLEATE
• Methyl salicylate
• Isoamyl o-hydroxybenzoate
• Tris(trimethylsilyl)phosphate
• Carbobenzoxyhydrazide
• Benzyl acetate
• Benzyl alcohol
• Methyl acrylate