N-BENZYLCINCHONINIUM CHLORIDE Chemical Properties

Melting point:

256 °C (dec.)(lit.)

refractive index 

168.5 ° (C=0.4, MeOH:H2O=1:5)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

slightly sol. in Methanol

form 

powder to crystaline

color 

White to Almost white

optical activity

[α]20/D +169°, c = 0.4 in H2O

BRN 

5232950

CAS DataBase Reference

69221-14-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich

N-BENZYLCINCHONINIUM CHLORIDE Usage And Synthesis

Chemical Properties

Solid

Uses

Phase-transfer catalyst involved in:

• Enantioselective alkylation of malonic diester with alkyl halides
• Hydrolysis of enol esters
• Asymmetric 6π electrocyclization for synthesis of functionalized indolines
• Asymmetric Michael addition
• Alkylation of monosubstituted indolinones with alkylhalides
• Asymmetric destruction and kinetic resolution of 1-benzylated Reissert compounds

Purification Methods

Recrystallise the chloride from isoPrOH, toluene or small volumes of H2O. It is a good chiral phase transfer catalyst [Julia et al. J Chem Soc, Perkin Trans 1 574 1981, Hughes et al. J Am Chem Soc 106 446 1984, Hughes et al. J Org Chem 52 4745 1987].

N-BENZYLCINCHONINIUM CHLORIDE(69221-14-3)Related Product Information

• Benzyltriethylammonium chloride
• Mepiquat chloride
• N-BENZYLQUINIDINIUM CHLORIDE
• N-BENZYLCINCHONINIUM CHLORIDE
• (R)(-)-2-BENZYLAMINO-1-BUTANOL
• N-Benzyl-N-methylpiperidinium chloride
• Tetraethylammonium Chloride
• Benzyltripropylammonium chloride
• Cinchonine
• 4-BUTYLPIPERIDINE
• CINCHONINE HYDROCHLORIDE
• 2,4-Dimethylpiperidine
• (R)-(+)-1-(4-PYRIDYL)ETHANOL
• N-Benzylcinchoninium chloride ,99%
• Methyltripropyl ammonium chloride
• 6-BENZYLAMINO-1-HEXANOL
• 2-HYDROXY-4-PYRIDYLETHYLAMINE
• 2-(3-METHYLPIPERIDIN-1-YL)PROPAN-1-OL