Borane-2-picoline complex Chemical Properties

Melting point:

48 °C

Density 

1.297 g/mL at 25 °C

Flash point:

100°(212°F)

storage temp. 

2-8°C

solubility 

Dichloromethane (Sparingly), Ethyl Acetate (Slightly)

form 

Solid

color 

White

Water Solubility 

Slightly sol. in water, cyclohexane, very sol. in methanol, THF, diglyme, and benzene

Sensitive 

Moisture Sensitive

InChIKey

ZMASBEFBIXMNCP-UHFFFAOYSA-N

Safety Information

Hazard Codes 

F,Xn,Xi

Risk Statements 

14/15-40-36/37/38-26

Safety Statements 

36/37-43-26-36/37/38-14/15

RIDADR 

UN 3130 6.1(4.3) / PGII

WGK Germany 

3

HazardClass 

4.3

PackingGroup 

II

HS Code 

29333990

Borane-2-picoline complex Usage And Synthesis

Uses

Environmentally benign reducing agent. Reactant for: Reductive amination. N-Benzyl-protection of amino acid derivatives by reductive alkylation. Reductive alkoxyamination.

Uses

Used as reactant for N-Benzyl-protection of amino acid derivatives by reductive alkylation, reductive alkoxyamination, as reducing agent for the labeling of oligosaccharides by reductive amination, synthesis of alkoxyamine derivatives, via reduction of oxime ethers, reductive amination reactions of C1-C10 aldehyde 2,4-dinitrophenylhydrazones, synthesis of various trifluoromethylated amino compounds and an alternative reagent for reductive aminations.

General Description

2-Methylpyridine borane complex is a nontoxic alternate to the reducing agent sodium cyanoborohydride.

reaction suitability

reagent type: reductant

Borane-2-picoline complex(3999-38-0)Related Product Information

• Methoxydiethylborane
• Borane-tetrahydrofuran complex
• 2,4,6-Collidine
• 2-Chloro-5-chloromethylpyridine
• 2,6-Lutidine
• 4-Methylpyridine
• INTERMEDIATES
• Azamethiphos
• 2-Picoline
• Boron nitride
• Boron
• Dimethylaminoborane
• Borane tert-butylamine complex
• 1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE
• 1,2,4,6-Tetraphenylpyridinium tetrafluoroborate
• N-BENZYL-2,4,6-TRIPHENYL PYRIDINIUM TETRAFLUOROBORATE
• Borane-2-picoline complex
• 2,6-DIETHYL-4-PHENYL-1-[3-(TRIFLUOROMETHYL)BENZYL]PYRIDINIUM TETRAFLUOROBORATE