Cyclopropanecarbonyl Chloride Chemical Properties

Melting point:

77.5-78.5 °C(Solv: hexane (110-54-3))

Boiling point:

119 °C(lit.)

Density 

1.152 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.452(lit.)

Flash point:

74 °F

storage temp. 

2-8°C

solubility 

soluble in Chloroform

form 

Liquid

Specific Gravity

1.1520

color 

Clear colorless to slightly yellow

Water Solubility 

decomposes

Sensitive 

Moisture Sensitive

BRN 

471286

Stability:

Moisture Sensitive

InChIKey

ZOOSILUVXHVRJE-UHFFFAOYSA-N

CAS DataBase Reference

4023-34-1(CAS DataBase Reference)

NIST Chemistry Reference

Cyclopropanecarboxylic acid chloride(4023-34-1)

EPA Substance Registry System

Cyclopropanecarbonyl chloride (4023-34-1)

Safety Information

Hazard Codes 

C,F

Risk Statements 

10-34-29-25-36-38

Safety Statements 

26-36/37/39-45-8-16

RIDADR 

UN 2920 8/PG 2

WGK Germany 

3

F 

10-21

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29162000

Toxicity

LD50 orally in Rabbit: 200 mg/kg

MSDS

• Language:English Provider:Cyclopropanecarbonyl chloride
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Cyclopropanecarbonyl Chloride Usage And Synthesis

Chemical Properties

clear colorless to slightly yellow liquid

Uses

Cyclopropanecarbonyl chloride can be used as an alkylating reagent in the preparation of some chemical building blocks such as formylcyclopropane, cyclopropanecarboxylic acid hydrazide, bis(cyclopropylcarbonyl) peroxide, 1-cyclopropanecarboxamide, 2-cyclopropylcarbonylcyclohexane-1,3-diones and cyclopropyl analog of triazolopiperazine-amides.

Purification Methods

If the IR shows OH bands, then some hydrolysis to the free acid must have occurred. In this case heat with oxalyl chloride at 50o for 2hours or SOCl2 for 30minutes, then evaporate and distil three times using a Dufton column (p 10). Store it in an inert dry atmosphere, preferably in sealed tubes. Strong IRRITANT. If it is free from OH bands, then just distil it in vacuo and store as before. [Jeffrey & Vogel J Chem Soc 1804 1948, Beilstein 9 IV 4.]

Cyclopropanecarbonyl Chloride(4023-34-1)Related Product Information

• Cyclopropanecarboxylic acid
• p-Toluoyl chloride
• 2-Fluorobenzoyl chloride
• 4-Chlorobenzoyl chloride
• Benzoyl chloride
• Thionyl chloride
• Ammonium chloride
• Choline chloride
• Dicyclopropane methylamine
• Calcium chloride
• Oxalyl chloride
• Cyclopropanesulfonyl chloride
• Sodium chloride
• Aminomethylcyclopropane
• Zinc chloride
• Potassium chloride
• Cyclopropanecarbonitrile
• Cyclopentanecarbaldehyde