BISNORCHOLENALDEHYDE Chemical Properties

Melting point:

159-160 °C

Boiling point:

459.4±14.0 °C(Predicted)

Density 

1.07±0.1 g/cm3(Predicted)

solubility 

Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

BISNORCHOLENALDEHYDE Usage And Synthesis

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

Uses

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

BISNORCHOLENALDEHYDE(3986-89-8)Related Product Information

• 20α-Acetoxy-4-pregnen-3-one
• (17α)-Pregn-4-ene-3,20-dione
• 4-PREGNEN-20-ALPHA-OL-3-ONE
• 4,9(11)-PREGNADIEN-3,20-DIONE
• 4-PREGNEN-20-BETA-OL-3-ONE
• 1,4-PREGNADIEN-3,20-DIONE
• Progesterone EP Impurity G
• Progesterone EP Impurity F
• Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
• 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one
• Androstenone hydrazone
• 17-Iodoandrosta-5,16-dien-3beta-ol
• tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
• CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester
• 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-
• N-(1-Cyclohexen-1-yl)morpholine
• Abiraterone
• Pregna-4,6-diene-3,20-dione