Methyl malonyl chloride Chemical Properties

Boiling point:

57-59 °C/12 mmHg (lit.)

Density 

1.273 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.432(lit.)

Flash point:

176 °F

storage temp. 

2-8°C

solubility 

soluble in Chloroform, Ethyl Acetate

pka

9.33±0.46(Predicted)

form 

Liquid

color 

Colorless

Specific Gravity

1.275

Water Solubility 

Reacts with water.

Sensitive 

Lachrymatory

BRN 

1754078

InChIKey

UTBCRHAMJFMIIR-UHFFFAOYSA-N

CAS DataBase Reference

37517-81-0(CAS DataBase Reference)

NIST Chemistry Reference

Methyl malonyl chloride(37517-81-0)

Safety Information

Hazard Codes 

C

Risk Statements 

34-36/37

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

8-10-19

Hazard Note 

Corrosive/Lachrymatory/Keep Cold

HazardClass 

8

PackingGroup 

II

HS Code 

29171900

MSDS

• Language:English Provider:Methyl malonyl chloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Methyl malonyl chloride Usage And Synthesis

Chemical Properties

Clear light yellow to yellow liquid

Uses

Methyl malonyl chloride is used as pharmaceutical intermediate. Used in anti-cancer drugs.

General Description

Methyl 3-chloro-3-oxopropionate reacts with 4-cyano-1,1′-biphenyl derivatives bearing ω-hydroxyalkyl substituents to yield liquid-crystalline linear malonates and cyanoacetates.

Methyl malonyl chloride(37517-81-0)Related Product Information

• Basic Violet 1
• Methyl acetate
• Diethyl malonate
• Paraquat dichloride
• Kresoxim-methyl
• Methylparaben
• Potassium 3-methoxy-3-oxopropanoate
• Acetonitrile
• Methyl acrylate
• Malonic acid
• Dimethyl malonate
• Methanol
• Malonyl chloride
• 3-Chloro-4-fluoro Methyl benzoate
• METHYL 3-CHLORO-4-HYDROXYBENZOATE
• S-(hydrogen malonyl)coenzyme A
• Methyl
• 4-Nitrobenzyl hydrogen malonate