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N-METHYLSUCCINIMIDE

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N-METHYLSUCCINIMIDE Basic information

Product Name:
N-METHYLSUCCINIMIDE
Synonyms:
  • 1-METHYL-2,5-PYRROLIDINEDIONE
  • 1-methyl-5-pyrrolidinedione
  • 1-Methyl-pyrrolidine-2,5-dione
  • 2,5-Pyrrolidinedione,1-methyl-
  • N-Methylsuccinimid
  • Succinimide, N-methyl-
  • N-METHYLSUCCINIMIDE
  • N-Methylsuccinimide, 98%+
CAS:
1121-07-9
MF:
C5H7NO2
MW:
113.11
EINECS:
628-414-2
Product Categories:
  • Carbonyl Compounds
  • Cyclic Imides
  • Organic Building Blocks
Mol File:
1121-07-9.mol
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N-METHYLSUCCINIMIDE Chemical Properties

Melting point:
61-70 °C(lit.)
Boiling point:
234-235 °C(lit.)
Density 
1.2416 (rough estimate)
refractive index 
1.4790 (estimate)
Flash point:
234-235°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
-1.34±0.20(Predicted)
color 
Off-White
Sensitive 
Moisture Sensitive
BRN 
110534
CAS DataBase Reference
1121-07-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-41
Safety Statements 
26-36/37
WGK Germany 
2
RTECS 
UY1028650
HS Code 
2925.19.9100

MSDS

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N-METHYLSUCCINIMIDE Usage And Synthesis

Chemical Properties

white crystals

Uses

N-Methylsuccinimide is used as a model compound to investigate the mechanism of enolization step by density-functional theory (DFT) calculations. N-Methylsuccinimide is a metabolite of N-methyl-2-pyrrolidone (NMP) and its presence in plasma and urine can be used as a biomarker of exposure to NMP

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 31, p. 4209, 1983 DOI: 10.1248/cpb.31.4209

General Description

N-Methylsuccinimide is a metabolite of N-methyl-2-pyrrolidone (NMP) and its presence in in plasma and urine can be used as a biomarker of exposure to NMP. Hydrogen bonded complexes between N-methylsuccinimide and phenols (pKa = 10.2 → 6) are investigated by infrared spectrometry.

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