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Dexamethasone Isonicotinate

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Dexamethasone Isonicotinate Basic information

Product Name:
Dexamethasone Isonicotinate
Synonyms:
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(4-pyridinylcarbonyl)oxy-, (11.beta.,16.alpha.)-
  • 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-isonicotinate
  • Desoximetasone Impurity 16 (Dexamethasone Isonicotinate)
  • Desoximetasone Impurity 16
  • 9-Fluoro-11β,17-dihydroxy-21-isonicotinoyloxy-16α-methylpregna-1,4-diene-3,20-dione
  • Auxiloson
  • Voren
  • isonicotin [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
CAS:
2265-64-7
MF:
C28H32FNO6
MW:
497.56
EINECS:
218-866-5
Mol File:
2265-64-7.mol
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Dexamethasone Isonicotinate Chemical Properties

Melting point:
256°C
Boiling point:
676.0±55.0 °C(Predicted)
Density 
1.1972 (estimate)
storage temp. 
2-8°C
solubility 
Practically insoluble in water, slightly soluble in anhydrous ethanol and in acetone.
pka
11.92±0.70(Predicted)
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Dexamethasone Isonicotinate Usage And Synthesis

Chemical Properties

White or almost white crystalline powder.

Uses

Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.

Definition

ChEBI: Dexamethasone 21-(4-Pyridinecarboxylate) is a corticosteroid hormone.

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