DBCO-PEG3-OH Chemical Properties

Boiling point:

777.1±60.0 °C(Predicted)

Density 

1.26±0.1 g/cm3(Predicted)

pka

14.36±0.10(Predicted)

InChI

InChI=1S/C27H32N2O6/c30-14-16-34-18-20-35-19-17-33-15-13-28-26(31)11-12-27(32)29-21-24-7-2-1-5-22(24)9-10-23-6-3-4-8-25(23)29/h1-8,30H,11-21H2,(H,28,31)

InChIKey

ALXJBBJGKMRACK-UHFFFAOYSA-N

SMILES

C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)NCCOCCOCCOCCO

DBCO-PEG3-OH Usage And Synthesis

Description

Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Hydroxy-PEG3-DBCO is a click chemistry reagent containing an azide group. Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].

References

[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910

DBCO-PEG3-OH(2566404-76-8)Related Product Information

• DBCO-PEG3-OTs
• DBCO-PEG3-Val-Cit-PAB-PNP
• DBCO-PEG3-amine
• DBCO-PEG3-Gly
• 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
• DBCO-PEG3-Mal
• DBCO-PEG3-F
• DBCO-PEG4-triethoxysilane
• Propanoic acid, 3-[2-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
• 4,7,10,13,16,19,22,25-Octaoxa-28-azadotricosanoic acid, 32-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-29,32-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
• DBCO-C6-acid
• DBCO-PEG2-amine
• DBCO-PEG4-maleimide
• DBCO-Acid
• DBCO-PEG1
• DBCO-PEG4-biotin
• DBCO-NHCO-PEG2-Biotin
• Ambient temperature