ROBINETIN Chemical Properties

Melting point:

326-328°C

Boiling point:

363.28°C (rough estimate)

Density 

1.3616 (rough estimate)

refractive index 

1.4790 (estimate)

storage temp. 

2-8°C

solubility 

DMSO (Sparingly), Methanol (Slightly, Heated)

form 

Solid

pka

6.82±0.40(Predicted)

color 

Yellow to Dark Yellow

LogP

2.550 (est)

Safety Information

Risk Statements 

22

Safety Statements 

22-45

RIDADR 

2811

ROBINETIN Usage And Synthesis

Uses

Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation[1][2][3][4][5].

Definition

ChEBI: A pentahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 7, 3, 4' and 5'.

References

[1] Fesen MR, et, al. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem Pharmacol. 1994 Aug 3;48(3):595-608. DOI:10.1016/0006-2952(94)90291-7
[2] Cushnie TPT, et, al. Antimicrobial activity of flavonoids. Int J Antimicrob Agents. 2005 Nov;26(5):343-56. DOI:10.1016/j.ijantimicag.2005.09.002
[3] Chaudhuri S, et, al. Binding of the bioflavonoid robinetin with model membranes and hemoglobin: Inhibition of lipid peroxidation and protein glycosylation. J Photochem Photobiol B. 2010 Jan 21;98(1):12-9. DOI:10.1016/j.jphotobiol.2009.10.002
[4] Birt DF, et, al. Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis. 1986 Jun;7(6):959-63. DOI:10.1093/carcin/7.6.959
[5] Manrique-de-la-Cuba MF, et, al. Theoretical study of the antioxidant capacity of the flavonoids present in the Annona muricata (Soursop) leaves. J Mol Model. 2019 Jun 25;25(7):200. DOI:10.1007/s00894-019-4083-7

ROBINETIN(490-31-3)Related Product Information

• Myricitrin
• Myricetin
• ROBINETIN
• SYRINGETIN-3-GALACTOSIDE
• 3,5,7-TRIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE
• SYRINGETIN-3-GLUCOSIDE
• SYRINGETIN
• ROBINETIN TRIMETHYL ETHER
• ROBINETIN,ROBINETIN(SH)
• ROBINETIN TRIMETHYLETHER(RG)
• 5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE
• CANNABISCITRIN
• 3-HYDROXY-7,3',4',5'-TETRAMETHOXYFLAVONE
• MYRICETIN 3,7-DIMETHYL ETHER
• EUROPETIN
• MYRICETIN-3-GALACTOSIDE
• LARICITRIN-3,5'-DI-O-GLUCOSIDE
• LARICITRIN-3,7,5'-TRI-O-GLUCOSIDE