3-Amino-9-ethylcarbazole Chemical Properties

Melting point:

85-88 °C(lit.)

Boiling point:

355C

Density 

1,15g/cm

refractive index 

1.6180 (estimate)

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly), Methanol (Slightly)

pka

4.99±0.30(Predicted)

form 

tablet

color 

Brown to Very Dark Brown

BRN 

174969

CAS DataBase Reference

132-32-1(CAS DataBase Reference)

NIST Chemistry Reference

9H-carbazol-3-amine, 9-ethyl-(132-32-1)

EPA Substance Registry System

3-Amino-9-ethylcarbazole (132-32-1)

Safety Information

Hazard Codes 

T

Risk Statements 

25-36/37/38-40-23/24/25-45

Safety Statements 

45-36/37/39-26-22-53

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

FE3590000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29339900

Hazardous Substances Data

132-32-1(Hazardous Substances Data)

MSDS

• Language:English Provider:9-Ethylcarbazol-3-amine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-Amino-9-ethylcarbazole Usage And Synthesis

Chemical Properties

3-Amino-9-ethylcarbazole is a brownish or tannish powder and chunks. It is utilized for producing dyes and pigments, as well as serving as an indicator for peroxidase in cells and a biological stain.

Uses

3-Amino-9-ethylcarbazole (AEC) has been used as a chromogen in immunohistochemistry to visualize the cells. It has also been used as a substrate in enzyme-linked immune absorbent spot (ELISpot).

Definition

ChEBI: 3-Amino-9-ethylcarbazole is a hydrochloride salt and free amine solid compound. It has been used to visualize the bound primary antibody by using a streptavidin method. It has also been used in visualizing tissue sections from tumour samples.

Preparation

Prepared by reducing 3-nitro-N-ethylcarbazole with sodium sulfide.

General Description

Tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Hazard

Questionable carcinogen; poison.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 3-Amino-9-ethylcarbazole emits toxic fumes.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Safety Profile

Suspected carcinogen with experimental carcinogenic data. Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx,.

Potential Exposure

Plant workers engaged in the manufacture of this compound and its use in pigment manufacture. Laboratory workers using this material in colorimetric enzyme assays and as a biological stain

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Waste Disposal

Incinerator equipped with a scrubber or thermal unit to reduce nitrogen oxides emissions.

3-Amino-9-ethylcarbazole(132-32-1)Related Product Information

• Glycine
• EC 2.6.1.2
• Bis(2-ethylhexyl)amine
• 2-Aminophenol
• Triethylamine
• 3-Aminopyridine
• 6-Aminocaproic acid
• ALTRENOGEST
• Triethanolamine
• Dibenzylamine
• N-Ethylmethylamine
• Tris(hydroxymethyl)aminomethane
• POLY(N-VINYLCARBAZOLE)
• 3-Ethyl-3-oxetanemethanol
• 9-Ethyl-3-nitrocarbazole
• REMASTRAL BLUE FFRL
• Carbazole
• N-Ethylcarbazole