2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE Chemical Properties

Melting point:

53-54 °C

Boiling point:

277.6±29.0 °C(Predicted)

Density 

1.222±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

Appearance

White to yellow Solid

CAS DataBase Reference

196799-45-8

Safety Information

Risk Statements 

52

HS Code 

2932990090

2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE Usage And Synthesis

Synthesis

The general procedure for the synthesis of 2,3-dihydrobenzofuran-7-carbaldehyde using 2,3-dihydrobenzofuran-7-methanol as starting material was as follows: 2,3-dihydrobenzofuran-7-methanol (9.76 g, 64.99 mmol) was mixed with manganese dioxide (45.2 g, 519.93 mmol) in toluene (250 mL), and the reaction was stirred for 3 hours at 60 °C. Upon completion of the reaction, manganese dioxide was removed by filtration and the filtrate was concentrated under reduced pressure. Subsequently, the precipitate precipitated was collected by filtration and washed with cooled hexane to give 2,3-dihydrobenzofuran-7-carbaldehyde (7.43 g, 50.1 mmol, 77% yield) as a light yellow solid.

References

[1] Patent: TW2016/2105, 2016, A. Location in patent: Paragraph 1203
[2] Patent: WO2007/25307, 2007, A2. Location in patent: Page/Page column 305 - 306
[3] Patent: WO2008/106139, 2008, A1. Location in patent: Page/Page column 475

2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE(196799-45-8)Related Product Information

• 2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE
• 2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID
• 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3(2H,9bH)-dione monosodium salt
• 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE
• 5-BROMO-2,3-DIHYDROBENZO[B]FURAN-7-CARBONYL CHLORIDE
• (+)-Usniacin
• (-)-USNIC ACID
• 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXYLIC ACID
• USNIC ACID
• 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE
• Zatosetron
• 5-BROMO-2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID
• 2,3-DIHYDRO-1-BENZOFURAN-5-CARBALDEHYDE
• furaquinocin B
• furaquinocin A
• ADR 851
• 7-BROMO-2,3-DIHYDRO-1-BENZOFURAN-5-CARBALDEHYDE
• 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-5-CARBALDEHYDE