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POPSO

Basic information Safety Supplier Related

POPSO Basic information

Product Name:
POPSO
Synonyms:
  • 1,4-Piperazinebis(2-hydroxy-1-propanesulfonic acid)
  • 3,3'-(1,4-Piperazinediyl)bis(2-hydroxy-1-propanesulfonic acid)
  • 3,3'-(Piperazine-1,4-diyl)bis(2-hydroxypropane-1-sulfonic acid)
  • β,β'-Dihydroxy-1,4-piperazinedi(1-propanesulfonic acid)
  • POPSO (Piperazine-1,4-bis(2-hydroxypropanesulfonic acid)dihydrat
  • β,β'-dihydroxypiperazine-1,4-dipropanesulphonic acid
  • Piperazine-1,4-bis(2-hydroxypropanesulfonic Acid) Dihydrate [Good's buffer component for biological research]
  • POPSO hydrate ,99%
CAS:
68189-43-5
MF:
C10H22N2O8S2
MW:
362.42
EINECS:
269-199-1
Product Categories:
  • Buffer
  • Biochemistry
  • Good's Buffers
Mol File:
68189-43-5.mol
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POPSO Chemical Properties

Melting point:
320°C
Density 
1.578±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
1 M NaOH: 0.1 M, clear, colorless
form 
Solid
color 
White powder
PH Range
7.2 - 8.5
pka
7.8(at 25℃)
BRN 
842252
InChI
InChI=1S/C10H22N2O8S2.2H2O/c13-9(7-21(15,16)17)5-11-1-2-12(4-3-11)6-10(14)8-22(18,19)20;;/h9-10,13-14H,1-8H2,(H,15,16,17)(H,18,19,20);2*1H2
InChIKey
PDSOJBZKKTTWHS-UHFFFAOYSA-N
SMILES
S(=O)(=O)(O)CC(O)CN1CCN(CC(O)CS(=O)(=O)O)CC1.O.O
CAS DataBase Reference
68189-43-5(CAS DataBase Reference)
EPA Substance Registry System
1,4-Piperazinedipropanesulfonic acid, .beta.,.beta.'-dihydroxy- (68189-43-5)
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Safety Information

Hazard Codes 
T
Risk Statements 
21-23/24/25-25-36/37/38
Safety Statements 
22-24/25-45-36/37/39-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29335990

MSDS

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POPSO Usage And Synthesis

Description

POPSO (Piperazine-1,4-bis(2-hydroxypropanesulfonic Acid) Dihydrate) is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5.

Chemical Properties

white powder

POPSOSupplier

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