Methyl indole-4-carboxylate Chemical Properties

Melting point:

68-71 °C(lit.)

Boiling point:

306.47°C (rough estimate)

Density 

1.1999 (rough estimate)

refractive index 

1.5060 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Methanol

form 

Crystalline Powder

pka

15.80±0.30(Predicted)

color 

Off-white to green

BRN 

141826

InChIKey

WEAXQUBYRSEBJD-UHFFFAOYSA-N

CAS DataBase Reference

39830-66-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Methyl indole-4-carboxylate Usage And Synthesis

Chemical Properties

off-white to green crystalline powder

Uses

• ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• ;Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells2• ;Reactant for preparation of inhibitor for β-tryptase3• ;Reactant for preparation of histamine H3 antagonists4• ;Reactant for preparation of JNK3 MAP kinase inhibitors5• ;Reactant for preparation of nucleosides6

Uses

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells
• Reactant for preparation of inhibitor for β-tryptase
• Reactant for preparation of histamine H3 antagonists
• Reactant for preparation of JNK3 MAP kinase inhibitors
• Reactant for preparation of nucleosides

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 1405, 1989 DOI: 10.1002/jhet.5570260533
Chemical and Pharmaceutical Bulletin, 29, p. 249, 1981 DOI: 10.1248/cpb.29.249

General Description

The IR and UV spectra of methyl indole-4-carboxylate was studied.

Methyl indole-4-carboxylate(39830-66-5)Related Product Information

• Methanol
• Indometacin
• Iodomethane
• Indole-3-acetic acid
• RESMETHRIN
• Basic Violet 1
• Indole
• Methylparaben
• Methyl 3-cyanoindole-4-carboxylate
• Indole-3-butyric acid
• Acetonitrile
• Methyl acrylate
• Ethyl 1H-indole-4-carboxylate
• 3-formyl-1H-Indole-4-carboxylic acid methyl ester
• Indole-4-carboxylic acid
• Indole-4-carboxaldehyde
• Indoline-2-carboxylic acid
• Indole-6-carboxylic acid