4-BROMO-BENZO[B]THIOPHENE Chemical Properties

Boiling point:

144 °C(Press: 20 Torr)

Density 

1.649±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

form 

solid

color 

White to off-white

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2934999090

4-BROMO-BENZO[B]THIOPHENE Usage And Synthesis

Synthesis

The traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene. 

Uses

4-bromobenzo [b] thiophene is an important intermediate in the drug ipiprazole for the treatment of schizophrenia.

4-BROMO-BENZO[B]THIOPHENE(5118-13-8)Related Product Information

• 4-BROMO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
• Thianaphthene
• Brexpiprazole-d8
• 4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butan-1-ol
• 4-BROMO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
• Brexpiprazole Impurity 20
• Brexpiprazole Impurity 36
• Brexpiprazole Impurity 5 HCl
• Brexpiprazole Impurity 2
• 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one
• Brexpiprazole Impurity 7
• Brexpiprazole Impurity 18
• Brexpiprazole Impurity 24
• Brexpiprazole Impurity 22
• (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE
• Brexpiprazole Impurity 21
• 8-(benzo[b]thiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride
• 5-HYDROXY-2(1H)-QUINOLINONE