Basic information Safety Supplier Related

Creatine ethyl ester hydrochloride

Basic information Safety Supplier Related

Creatine ethyl ester hydrochloride Basic information

Product Name:
Creatine ethyl ester hydrochloride
Synonyms:
  • CREATINE ETHYL ESTER HYDROCHLORIDE
  • CREATINE ETHYL ESTER HCL (P)
  • Creatine ethyl ester hydrochloridel
  • Ethyl N-carbamimidoyl-N-methylglycinate hyd
  • CREATINE ETHYL ESTER HCL(SH)
  • Ethyl 2-(1-Methylguanidino)acetate hydrochloride
  • Glycine,N-(aMinoiMinoMethyl)-N-Methyl-, ethyl ester, hydrochloride (1:1)
  • Creatine ethyl ester hydrochloride[3]
CAS:
15366-32-2
MF:
C6H14ClN3O2
MW:
195.65
EINECS:
000-000-0
Mol File:
15366-32-2.mol
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Creatine ethyl ester hydrochloride Chemical Properties

Melting point:
162-165°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
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Creatine ethyl ester hydrochloride Usage And Synthesis

Synthesis

Creatine ethyl ester hydrochloride is prepared by the reaction of ethanol and creatine. The specific synthesis steps are as follows:
Phosphorochloridic acid (2.0-2.5 equivalents to creatine) was added dropwise to a suspension of creatine in 10 mL of ethanol at 0° C. The reaction mixture was stirred for 15 min at 0° C. and the temperature then raised to 60° C. and stirred for 30 min. The reaction mixture was then cooled to provide 1.7 g of the hydrochloride salt of title compound (24) (73percent yield) as a white solid. 1H NMR (CD3OD, 400 MHz): δ 4.20-4.30 (m, 4H), 3.16(s, 3H, creatinine NCH3), 3.08 (s, 3H, CBE NCH3), 1.31 (d, J=6.8 Hz), (CBE/creatinine=9:1).

Creatine ethyl ester hydrochlorideSupplier

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