N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Chemical Properties

Melting point:

148-150℃

Boiling point:

501.5±60.0 °C(Predicted)

Density 

1.29±0.1 g/cm3(Predicted)

storage temp. 

Amber Vial, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

14.11±0.10(Predicted)

color 

Yellow

Stability:

Light Sensitive

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea Usage And Synthesis

Uses

N-Cyano-N’-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea (Cimetidine EP Impurity A) is a Cimetidine (C441650) related impurity. Cimetidine (C441650), a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output. Also used in the preparation of histamine H2 receptor antagonists.

N-Cyano-N-[2-(5-methylimidazole-4-methylthio)ethyl]-S-methyl isothiourea(52378-40-2)Related Product Information

• guanylurea cimetidine
• Cimetidine Impurity 3
• Cimetidine Impurity 2
• Cimetidine Impurity 12
• CIMETIDINE DIHYDROCHLORIDE IMP D
• N-cyano-N',N''-dimethylguanidine
• N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]carbamimidic acid methyl ester
• 2-cyano-1,3-bis(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
• N-Cyano-3-(cyanoaMino)-N'-Methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-iMidaMide (CiMetidine IMpurity)
• Cimetidine Amide Dihydrochloride
• CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE
• N-CYANO-N',N'-DIMETHYLGUANIDINE
• 2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethylamine dihydrochloride
• (5-Ethyl-1H-imidazol-4-yl)methanol
• Cimetidine
• Tinidazole
• 4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole
• DIMETHYLCYANAMIDE