Buclosamide Chemical Properties

Melting point:

90-92°

Boiling point:

366.6±32.0 °C(Predicted)

Density 

1.1769 (rough estimate)

refractive index 

1.5500 (estimate)

pka

7.43±0.35(Predicted)

MSDS

• Language:English Provider:Buclosamide

Buclosamide Usage And Synthesis

Originator

Fungit,Dragon

Definition

ChEBI: Buclosamide is a member of salicylamides.

Manufacturing Process

4-Chloro-2-hydroxy-benzoic acid n-butyl-amide
A mixture consisting of 114 g of 4-chloro-2-hydroxy-benzoic acid n-butylester, 64 grams of methanol and 130 g of n-butyl-amine is heated for 22 hours at 80°C; then the parts volatile up to 130°C are distilled off under reduced pressure. The residue crystallizing in the cold is dissolved in 200 ml of methanol and the solution obtained is slowly added dropwise and while stirring into dilute hydrochloric acid, if necessary, after treatment with animal charcoal. The precipitate which is at first semi-solid soon crystallizes completely. It is filtered with suction, washed with dilute hydrochloric acid, then thoroughly washed again with water, and the product obtained in good yield is dried in the air. After having been recrystallized twice from carbon tetrachloride the 4-chloro-2-hydroxybenzene acid n-butylamide melts at 90- 92°C.

Therapeutic Function

Antifungal

Buclosamide(575-74-6)Related Product Information

• Buprofezin
• Niclosamide
• Chlorantraniliprole
• tert-Butylchlorodiphenylsilane
• Niclosamide ethanolamine salt
• Chloroacetamide
• Salicylhydrazide
• tert-Butyldimethylsilyl chloride
• Salicylamide
• 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
• Dibutyl phthalate
• BUTYL OLEATE
• Metoclopramide hydrochloride
• Oxyclozanide
• Moclobemide
• Cyhalofop-butyl
• Difluorochloromethane
• 5-chloro-2-[(4-methylpiperidin-1-yl)carbonyl]phenol