ChemicalBook > Product Catalog > API > Antipyretic analgesics > Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) > bucolome
bucolome
bucolome Basic information
- Product Name:
- bucolome
- Synonyms:
-
- bucolome
- Bucolomum [INN-Latin]
- 1-Cyclohexyl-5-butyl-2,4,6-trioxoperhydropyrimidine
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-butyl-1-cyclohexyl-
- 5-Butyl-1-cyclohexyl-2,4,6-trioxoperhydropyrimidine
- 5-Butyl-1-cyclohexyl-2,4,6-trioxoperhydroxyprimidine
- 5-Butyl-1-cyclohexylbarbituric acid
- 5-n-Butyl-1-cyclohexyl-2,4,6-trioxoperhydropyrimidine
- CAS:
- 841-73-6
- MF:
- C14H22N2O3
- MW:
- 266.34
- EINECS:
- 2126661
- Mol File:
- 841-73-6.mol
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bucolome Chemical Properties
- Melting point:
- 84°
- Boiling point:
- bp0.8 185-187°
- Density
- 1.0807 (rough estimate)
- refractive index
- 1.5110 (estimate)
- pka
- 5.71±0.40(Predicted)
- form
- Solid
- color
- White to off-white
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bucolome Usage And Synthesis
Uses
Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent.
Definition
ChEBI: 5-butyl-1-cyclohexylbarbituric acid is a member of barbiturates.
IC 50
CYP2
References
[1] Takahashi H, et al. Pharmacokinetic interaction between warfarin and a uricosuric agent, bucolome: application of In vitro approaches to predicting In vivo reduction of (S)-warfarin clearance. Drug Metab Dispos. 1999 Oct;27(10):1179-86. PMID:10497145
bucolomeSupplier
ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel
- 18149758185
- sales-cpd@caerulumpharma.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Dideu Industries Group Limited
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
Shaanxi Dideu Medichem Co. Ltd
- Tel
- +86-29-87569262 +86-15003564040
- 1087@dideu.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com