cyclovalone
cyclovalone Basic information
- Product Name:
- cyclovalone
- Synonyms:
-
- DIVANILLYLIDENECYCLOHEXANONE
- 2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexan-1-one
- 2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone
- Divanillydene cyclohexanone
- Flavugal
- Vanilone
- 2,6-Bis((4-hydroxy-3-methoxyphenyl)methylene)cyclohexan-1-one
- Aids057932
- CAS:
- 579-23-7
- MF:
- C22H22O5
- MW:
- 366.41
- EINECS:
- 209-438-9
- Mol File:
- 579-23-7.mol
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cyclovalone Chemical Properties
- Melting point:
- 178-179°
- Boiling point:
- 595.5±50.0 °C(Predicted)
- Density
- 1.292±0.06 g/cm3(Predicted)
- solubility
- Acetone (Slightly, Sonicated), DMSO (Slightly)
- form
- Solid
- pka
- 9.44±0.35(Predicted)
- color
- Yellow to Very Dark Yellow
- Stability:
- Light Sensitive
- LogP
- 4.470 (est)
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cyclovalone Usage And Synthesis
Uses
2,6-Divanillylidenecyclohexanone (cas# 579-23-7) is used to make a nanofiber which is found to have anti-bacterial and anti-cancer activity.
Definition
ChEBI: Cyclovalone is a diarylheptanoid.
in vivo
Cyclovalone (9.5-38 mg/kg, p.o. for 14 days) ist a prostate specific antagonist without significant toxicity in BALB/c mice[2].
| Animal Model: | BALB/c mice[2] |
| Dosage: | 9.5-38 mg/kg/day |
| Administration: | p.o. for 14 days |
| Result: | Reduced weight of ventral prostate in a dose-dependent manner. |
| Animal Model: | PC-3 xenografted athymic BALB/c nude mice[2] |
| Dosage: | 38 mg/kg |
| Administration: | p.o. for 20 days |
| Result: | Inhibited tumor growth without toxicity. |
cyclovaloneSupplier
China DongFan Chemical Co.,LTD
- Tel
- 86-0571-85151182
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
- Tel
- 021-51816796-820 13611835272
- sales2@sunwaypharm.com
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
- Tel
- 029-029-81120477 17792793610
- 1033@dideu.com
TargetMol Chemicals Inc.
- Tel
- 15002134094
- marketing@targetmol.cn
Merck KGaA
- Tel
- 21-20338288
- ordercn@merckgroup.com