Escin, monosodium salt Chemical Properties

Melting point:

250-252 °C

solubility 

≥24.5mg/ml in DMSO

form 

Powder

color 

White to off-white

Escin, monosodium salt Usage And Synthesis

Description

Escin, monosodium salt is a natural product obtained from the plant horse chestnut. It is used in the treatment of chronic venous insufficiency, where it has been shown to have anti-inflammatory and anti-thrombotic effects. It is a mixture of polysulphated disaccharides that can be purified by HPLC.

Chemical Properties

Sodium saponin salt obtained from the extract of the dried mature fruit (Solanum serrata) of the Castanea plant.

Uses

Monosodium salt of Escin (E658790), has been used as a treatment for ischemic damage, hemorrhoids, and trauma or for recovery post-operation. Also used in the treatment of adenocarcinoma cell lines.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Na2O. See also SAPONIN and other escin entries.

in vivo

target

NO | TNF-α | IL Receptor | Bcl-2/Bax | VEGFR

Escin, monosodium salt (20977-05-3)Related Product Information

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