Isoliensinine
Isoliensinine Basic information
- Product Name:
- Isoliensinine
- Synonyms:
-
- Isoliensinine
- (+)-Isoliensinin
- (1R)-1,2,3,4-Tetrahydro-1-[[4-hydroxy-3-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenyl]methyl]-6-methoxy-2-methyl-7-isoquinolinol
- (1R)-1-[[4-hydroxy-3-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
- 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-hydroxy-3-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenyl]methyl]-6-methoxy-2-methyl-, (1R)-
- Isoliensinine USP/EP/BP
- (+)-Isoliensinine
- (1R)-1-(4-hydroxy-3-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-m...
- CAS:
- 6817-41-0
- MF:
- C37H42N2O6
- MW:
- 610.74
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 6817-41-0.mol
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Isoliensinine Chemical Properties
- Melting point:
- 69-71℃
- Boiling point:
- 723.1±60.0 °C(Predicted)
- Density
- 1.218
- storage temp.
- 2-8°C(protect from light)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- pka
- 9.28±0.45(Predicted)
- color
- White
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Isoliensinine Usage And Synthesis
Description
Tomita and his co-workers have obtained this bisisoquinoline alkaloid from the embryo of the seeds of Nelumbo nucifera Gaertn. The base has [α]29D + 49.3° (Me2CO) and - 43.3° (CHC13 ). The hydrochloride tetrahydrate forms colourless crystals, m.p. l85-6°C (dry); the perchlorate monohydrate has m.p. 200-3°C (dry); [α]22D - 70° (Me2CO) and the styphnate of the O,O-dimethyl ether, also crystalline, has m.p. l33-5°C; [α]27D - 81.5° (Me2CO). Three methoxyl, two hydroxyl and two methylimino groups are present.
Uses
(+)-Isoliensinine is an alkaloid which displays activation of AMP-activated kinase and regulation of PPARγ receptors.
Definition
ChEBI: Isoliensinine is a member of isoquinolines.
References
Tomita et aI., Tetrahedron Lett., 2637,3374 (1964)
IsoliensinineSupplier
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