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ABD-F

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ABD-F Basic information

Product Name:
ABD-F
Synonyms:
  • 4-Fluoro-7-sulfobenzofurazan
  • [=4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for DeterMination of Thiols]
  • ABD-F 
  • 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol
  • 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, 98%, derivatization grade
  • 7-Fluorobenzoc1,2,5oxadiazole-4-sulfonamide
  • 4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, derivatization grade
  • ABD-F
CAS:
91366-65-3
MF:
C6H4FN3O3S
MW:
217.18
Product Categories:
  • Chemical and pharmaceutical intermediates
  • pharmaceutical intermediates
  • Analytical Chemistry
  • Fluorescence Detection (HPLC Labeling Reagents)
  • HPLC Labeling Reagents
  • Mercapto Group Labeling Reagents for Fluorescence HPLC
  • Fluorescent Labels and Indicators
  • Fluorescent Labels & Indicators
  • MTS & Sulfhydryl Active Reagents
Mol File:
91366-65-3.mol
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ABD-F Chemical Properties

Melting point:
143-145°C
Boiling point:
408.8±55.0 °C(Predicted)
Density 
1.724±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble
form 
White to yellow crystalline powder.
pka
9.08±0.30(Predicted)
color 
Off-White to Pale Yellow
BRN 
5035147
Stability:
Light Sensitive
InChIKey
XROXHZMRDABMHS-UHFFFAOYSA-N
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Safety Information

Hazard Codes 
Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36/37/39-24/25
WGK Germany 
3
3-10
Hazard Note 
Irritant
HS Code 
29350090

MSDS

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ABD-F Usage And Synthesis

Chemical Properties

Light Yellow Solid

Uses

Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC.

Uses

A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm)

Uses

Reagent for fluorimetric assay of thiols.

General Description

4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography.

ABD-FSupplier

Suzhou Ran enzyme Biotechnology Co., Ltd. Gold
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0512-0512-62793604 18015430729
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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Alfa Aesar
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400-6106006
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saleschina@alfa-asia.com