ABD-F
ABD-F Basic information
- Product Name:
- ABD-F
- Synonyms:
-
- 4-Fluoro-7-sulfobenzofurazan
- [=4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for DeterMination of Thiols]
- ABD-F 
- 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol
- 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, 98%, derivatization grade
- 7-Fluorobenzoc1,2,5oxadiazole-4-sulfonamide
- 4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, derivatization grade
- ABD-F
- CAS:
- 91366-65-3
- MF:
- C6H4FN3O3S
- MW:
- 217.18
- Product Categories:
-
- Chemical and pharmaceutical intermediates
- pharmaceutical intermediates
- Analytical Chemistry
- Fluorescence Detection (HPLC Labeling Reagents)
- HPLC Labeling Reagents
- Mercapto Group Labeling Reagents for Fluorescence HPLC
- Fluorescent Labels and Indicators
- Fluorescent Labels & Indicators
- MTS & Sulfhydryl Active Reagents
- Mol File:
- 91366-65-3.mol
ABD-F Chemical Properties
- Melting point:
- 143-145°C
- Boiling point:
- 408.8±55.0 °C(Predicted)
- Density
- 1.724±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- White to yellow crystalline powder.
- pka
- 9.08±0.30(Predicted)
- color
- Off-White to Pale Yellow
- BRN
- 5035147
- Stability:
- Light Sensitive
- InChIKey
- XROXHZMRDABMHS-UHFFFAOYSA-N
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36/37/39-24/25
- WGK Germany
- 3
- F
- 3-10
- Hazard Note
- Irritant
- HS Code
- 29350090
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
ABD-F Usage And Synthesis
Chemical Properties
Light Yellow Solid
Uses
Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC.
Uses
A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm)
Uses
Reagent for fluorimetric assay of thiols.
General Description
4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography.
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