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2-METHOXYETHYL CHLOROFORMATE

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2-METHOXYETHYL CHLOROFORMATE Basic information

Product Name:
2-METHOXYETHYL CHLOROFORMATE
Synonyms:
  • 2-Methoxyethyl chloroformate, tech. 85%
  • (2-Methoxyethoxy)carbonyl chloride
  • (Chloro)(2-methoxyethoxy)methanone
  • 2-methoxyethyl carbonochloridate
  • chlorocarbonic acid 2-methoxyethyl ester
  • Chloroformic Acid 2-Methoxyethyl Ester Ethylene Glycol Monomethyl Ether Chloroformate
  • CHLOROFORMIC ACID 2-METHOXYETHYL ESTER
  • ETHYLENE GLYCOL MONOMETHYL ETHER CHLOROFORMATE
CAS:
628-12-6
MF:
C4H7ClO3
MW:
138.55
EINECS:
211-026-9
Product Categories:
  • Acid Halides
  • Building Blocks
  • Acid Halides
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • CHLOROFORMATES
  • Carbonyl Compounds
  • Organic Building Blocks
Mol File:
628-12-6.mol
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2-METHOXYETHYL CHLOROFORMATE Chemical Properties

Boiling point:
157-158 °C(lit.)
Density 
1.192 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.4200(lit.)
Flash point:
138 °F
storage temp. 
2-8°C
solubility 
Soluble in most organic solvents.
form 
clear liquid
color 
Colorless to Light yellow
Sensitive 
Moisture Sensitive
CAS DataBase Reference
628-12-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2920 8/PG 2
WGK Germany 
3
10-21
HS Code 
2918.99.5000
HazardClass 
6.1
PackingGroup 
II

MSDS

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2-METHOXYETHYL CHLOROFORMATE Usage And Synthesis

Uses

Reactant for:• ;Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase1• ;Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction2• ;Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN3• ;Preparation of amino carboxamidobenzothiazoles as Lck inhibitors4• ;Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add st

Uses

2-methoxyethyl chloroformate was used to produce di-2-dimethoxyethyl hydrazine carboxylate(alternative reagent for the mitsunobu reaction).

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