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ChemicalBook >  Product Catalog >  Organic Chemistry >  Carboxylic acids and derivatives >  Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI)

Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI)

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Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI) Basic information

Product Name:
Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI)
Synonyms:
  • Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI)
  • BOC-(S)-HABA
  • (2S)-4-[[(tert-Butoxy)carbonyl]amino]-2-hydroxybutanoic acid
  • Boc-s-HABA Butanoic acid,4-[[(1,1-diMethylethoxy)carbonyl]aMino]-2-hydroxy-, (2S)- (9CI)
  • Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy
  • N-Boc-(S)-4-amino-2-hydroxybutanoic acid
  • (S)-4-(Boc-amino)-2-hydroxybutanoic Acid
  • (S)-4-[(tert-butoxycarbonyl)amino]-2-hydroxybutanoic acid
CAS:
207305-60-0
MF:
C9H17NO5
MW:
219.24
Product Categories:
  • N-BOC
Mol File:
207305-60-0.mol
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Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI) Chemical Properties

Boiling point:
422.8±35.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
pka
3.74±0.10(Predicted)
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Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-, (2S)- (9CI) Usage And Synthesis

Uses

(S)-4-(tert-Butoxycarbonylamino)-2-hydroxybutyric Acid is an intermediate in the synthesis of Plazomicin Sulfate (P579505), the acidic salt of Plazomicin (P579500). Plazomicin is a neoglycoside antibiotic with activity against a broad range of Gram-positive and Gram-negive pathogens. Plazomicin showed potent in vitro activity against multidrug-resistant Klebsiella pneumoniae and Escherichia coli.

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