BZ-PHE-VAL-ARG-AMC Chemical Properties

storage temp. 

−20°C

form 

Solid

color 

White to off-white

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

BZ-PHE-VAL-ARG-AMC Usage And Synthesis

Uses

Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate[1][2].

References

[1] Vasiljeva O, et al. Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett. 2005 Feb 14;579(5):1285-90. DOI:10.1016/j.febslet.2004.12.093
[2] Vasiljeva O, et al. Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry. 2003 Nov 25;42(46):13522-8. DOI:10.1021/bi035355k

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