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3-Nitro-2-pyridinol

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3-Nitro-2-pyridinol Basic information

Product Name:
3-Nitro-2-pyridinol
Synonyms:
  • 2-HYDROXY-3-NITROPYRIDINE
  • AURORA KA-2996
  • 3-NITROPYRIDIN-2-OL
  • 3-NITRO-2-PYRIDONE
  • 3-NITRO-2-PYRIDINOL
  • 3-NITRO-2-HYDROXYPYRIDINE
  • 3-NITRO-2(1H)-PYRIDONE
  • 3-NITRO-2(1H)-PYRIDINONE
CAS:
6332-56-5
MF:
C5H4N2O3
MW:
140.1
EINECS:
228-709-2
Product Categories:
  • NITRO
  • Pyridine
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Pyridines
  • Pyridines derivates
Mol File:
6332-56-5.mol
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3-Nitro-2-pyridinol Chemical Properties

Melting point:
212 °C (dec.) (lit.)
Boiling point:
256.56°C (rough estimate)
Density 
1.5657 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
8.37±0.10(Predicted)
color 
yellow
BRN 
124474
InChIKey
BOAFCICMVMFLIT-UHFFFAOYSA-N
CAS DataBase Reference
6332-56-5(CAS DataBase Reference)
NIST Chemistry Reference
2-Hydroxy-3-nitropyridine(6332-56-5)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-36-45-36/37/39
WGK Germany 
3
RTECS 
UU7718000
10
HazardClass 
IRRITANT, IRRITANT-HARMFUL
HS Code 
29333990

MSDS

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3-Nitro-2-pyridinol Usage And Synthesis

Chemical Properties

yellow to yellow-brown cryst. powder or needles

Uses

2-Hydroxy-3-nitropyridine was used in the synthesis of:

  • 3-nitro-2-pyridyl β-D-galactoside
  • 3-nitro-2-pyridyl N-acetyl-β-D-glucosaminide
  • 5-amino-6-chloro-3-iodopyridine

Synthesis Reference(s)

Tetrahedron Letters, 12, p. 2211, 1971 DOI: 10.1016/S0040-4039(01)96822-4

General Description

2-Hydroxy-3-nitropyridine reacts with phosphorus pentachloride and phosphoryl chloride to yield 2-chloro-3-nitropyridine.

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