5-Amino-8-hydroxyquinoline
5-Amino-8-hydroxyquinoline Basic information
- Product Name:
- 5-Amino-8-hydroxyquinoline
- Synonyms:
-
- 5-AMINO-8-HYDROXYQUINOLINE
- 5-Amino-8-hydroxyqui
- 5-Amino-8-hydroxyquinoline HClsalt
- 5-Aminoquinoline-8-ol
- CAS:
- 13207-66-4
- MF:
- C9H8N2O
- MW:
- 160.17
- EINECS:
- 1533716-785-6
- Mol File:
- 13207-66-4.mol
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5-Amino-8-hydroxyquinoline Chemical Properties
- Melting point:
- 236-238 °C (decomp)(Solv: hydrochloric acid, 20% (7647-01-0))
- Boiling point:
- 408.3±35.0 °C(Predicted)
- Density
- 1.363±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- Solid
- pka
- 5.65±0.10(Predicted)
- color
- Brown to black
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5-Amino-8-hydroxyquinoline Usage And Synthesis
Uses
5-Amino-8-hydroxyquinoline (5A8HQ), a potential anticancer candidate, has promising proteasome inhibitory activity.
References
[1] Ruankham W, et al. In silico and multi-spectroscopic analyses on the interaction of 5-amino-8-hydroxyquinoline and bovine serum albumin as a potential anticancer agent. Sci Rep. 2021 Oct 12;11(1):20187. DOI:10.1038/s41598-021-99690-2
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