H-LYS-GLN-ALA-GLY-ASP-VAL-OH Chemical Properties

storage temp. 

-20°C

form 

powder

color 

white to off-white

Sequence

Lys-Gln-Ala-Gly-Asp-Val

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

H-LYS-GLN-ALA-GLY-ASP-VAL-OH Usage And Synthesis

Uses

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].

Definition

ChEBI: Lys-Gln-Ala-Gly-Asp-Val is an oligopeptide.

Biochem/physiol Actions

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide used to study adhesion of platelets to neutrophils via the integrin glycoproteins gpIIb/IIIa.

References

[1] Dong CL, et al. The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials. 2012 Mar;33(9):2593-9. DOI:10.1016/j.biomaterials.2011.12.020
[2] Mann BK, et al. Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. Biomaterials. 2001 Mar;22(5):439-44. DOI:10.1016/s0142-9612(00)00196-4

H-LYS-GLN-ALA-GLY-ASP-VAL-OH(80755-87-9)Related Product Information

• HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL
• H-ASP-VAL-OH
• H-LYS-GLN-ALA-GLY-ASP-VAL-OH
• FIBRINOGEN GAMMA-CHAIN (397-411)