sulfo-Cyanine5.5 tetrazine
sulfo-Cyanine5.5 tetrazine Basic information
- Product Name:
- sulfo-Cyanine5.5 tetrazine
- Synonyms:
-
- sulfo-Cyanine5.5 tetrazine
- MW:
- 0
- Mol File:
- Mol File
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sulfo-Cyanine5.5 tetrazine Chemical Properties
- solubility
- good in water, DMF, DMSO
- Appearance
- dark blue powder
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sulfo-Cyanine5.5 tetrazine Usage And Synthesis
Description
sulfo-Cyanine5.5 is a water-soluble, hydrophilic far-red fluorophore, an analog of Cy5.5®. Like other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient, giving rise to its bright fluorescence. The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore and minimize non-specific binding.
This reagent contains tetrazine moiety that reacts with trans-cyclooctenes, cyclopropenes, and some strained cyclooctynes to form stable conjugates via an inverted electron demand [4+2]-cycloaddition (IEDDA).
The reagent possesses high aqueous solubility and hydrophilicity and is recommended for labeling biomolecules in an aqueous environment.
Abs/Em Maxima
673/691 nm
Fluoresene quantum yield
0.21
Extinction Coefficient
211000
CF260
0.09
CF280
0.11