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O-PHOSPHO-L-TYROSINE

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O-PHOSPHO-L-TYROSINE Basic information

Product Name:
O-PHOSPHO-L-TYROSINE
Synonyms:
  • H-TYR(H2PO3)-OH
  • H-TYR(P)-OH
  • H-TYR(PO3H2)-OH
  • L-3-[4-HYDROXYPHENYL]ALANINE 4'-PHOSPHATE
  • L-TYROSINE O-PHOSPHATE
  • H-Tyr(PO3)-OH
  • H-L-Tyr(PO3H2)-OH
  • L-Phosphotyrosine, (S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic acid
CAS:
21820-51-9
MF:
C9H12NO6P
MW:
261.17
Product Categories:
  • Amino Acids
  • Biochemistry
  • Biological-modified Amino Acids
  • Amino Acids & Derivatives
  • Aromatics
  • Chiral Reagents
  • Phosphorylating and Phosphitylating Agents
Mol File:
21820-51-9.mol
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O-PHOSPHO-L-TYROSINE Chemical Properties

Melting point:
226-227°C
Boiling point:
521.7±60.0 °C(Predicted)
Density 
1.591±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Aqueous Acid (Slightly), Water (Slightly, Sonicated)
form 
Solid
pka
1.24±0.30(Predicted)
color 
White to Off-White
BRN 
3150815
CAS DataBase Reference
21820-51-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
21/22
Safety Statements 
36/37
WGK Germany 
3
10-21
HS Code 
29225090

MSDS

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O-PHOSPHO-L-TYROSINE Usage And Synthesis

Chemical Properties

White Solid

Uses

O-Phospho-L-tyrosine is used in the study of tyrosine-phosphorylation, which has been linked to the malignant transformation of cells by various RNA tumor viruses. Plays a role in signal transduction.

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid that is L-tyrosine phosphorylated at the phenolic hydroxy group.

Purification Methods

Purify it by recrystallisation from H2O or H2O/EtOH. [Levene & Schormüller J Biol Chem 100 583 1933, Posternak & Graff Helv Chim Acta 28 1258 1945, Beilstein 14 III 1510.]

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