Aminoguanidine bicarbonate Chemical Properties

Melting point:

170-172 °C (dec.)(lit.)

Density 

1,6 g/cm³

storage temp. 

Store below +30°C.

solubility 

H2O: soluble2.7g/L at 20°C

form 

Crystalline Powder

pka

6.19[at 20 ℃]

color 

White to off-white

PH

8.9 (5g/l, H2O, 20℃)

Water Solubility 

<5 g/L (20 ºC)

BRN 

3569869

InChIKey

OTXHZHQQWQTQMW-UHFFFAOYSA-N

LogP

-6.61 at 25℃

CAS DataBase Reference

2582-30-1(CAS DataBase Reference)

EPA Substance Registry System

Carbonic acid, compd. with hydrazinecarboximidamide (1:1) (2582-30-1)

Safety Information

Hazard Codes 

Xi,Xn,N

Risk Statements 

52/53-43-36/37/38-20/21/22-51/53

Safety Statements 

22-24/25-37-24-36-26-36/37

RIDADR 

UN3077

WGK Germany 

2

RTECS 

FG1772000

Autoignition Temperature

245 °C

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29280090

Toxicity

LD50 orally in Rabbit: > 5000 mg/kg

MSDS

• Language:English Provider:Aminoguanidine bicarbonate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Aminoguanidine bicarbonate Usage And Synthesis

Chemical Properties

White to off-white crystalline powder. It is almost insoluble in water, alcohol and other acids.

Uses

Aminoguanidine bicarbonate (AGB) is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications. It is used in the synthesis of antitumor agents and antileukemic activity. Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.

Application

Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase). Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.

Biochem/physiol Actions

Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.

Synthesis

A synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate.

storage

+4°C

Aminoguanidine bicarbonate(2582-30-1)Related Product Information

• Sodium carbonate
• Ethylene carbonate
• Ammonium carbonate
• Potassium bicarbonate
• Hydrogen
• Calcium carbonate
• Sodium bicarbonate
• Phenylguanidine carbonate salt
• Zinc carbonate
• AMINOGUANIDINE HEMISULFATE
• Barium carbonate
• Diethyl carbonate
• AMINOACETONITRILE HYDROGEN SULFATE
• Ammonium bicarbonate
• Guanidine carbonate
• Benzyl carbamate
• Sulfamic acid
• AMINOGUANIDINE