ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > Loperamide
Loperamide
Loperamide Basic information
- Product Name:
- Loperamide
- Synonyms:
-
- loperamide oxide
- R 58425
- trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide
- trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate
- Loperamide EP Impurity F
- 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide
- LoperaMide-d6 N-Oxide
- Loperamide impurity-F(EP)
- CAS:
- 106900-12-3
- MF:
- C29H33ClN2O3
- MW:
- 493.04
- Product Categories:
-
- Amines
- Drug Analogues
- Heterocycles
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 106900-12-3.mol
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Loperamide Chemical Properties
- solubility
- Practically insoluble in water, freely soluble in alcohol and in methylene chloride.
- pka
- 12.94±0.20(Predicted)
- Stability:
- Hygroscopic
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Loperamide Usage And Synthesis
Chemical Properties
White or almost white powder, slightly hygroscopic.
Uses
Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
Uses
Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
Definition
ChEBI: Loperamide oxide is a diarylmethane.
LoperamideSupplier
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Loperamide(106900-12-3)Related Product Information
- 1-(4-CHLORO-PHENYL)-3-DIMETHYLAMINO-PROPAN-1-OL
- (R)-1-(4-CHLOROPHENYL)-1-PROPANOL
- fenpipramide
- 4-(4-CHLOROPHENYL)PIPERIDINE
- Alverine
- Trimethylamine N-oxide
- 4-(4-Chlorophenyl)piperidin-4-ol
- (Diphenyl-3,3 propyl)-1 phenyl-4 piperidine chlorhydrate [French]
- Loperamide
- Trimethylamine N-oxide dihydrate
- 2,2-DIPHENYLPROPYLAMINE HYDROCHLORIDE
- TRIETHYLAMINE N-OXIDE
- DIPHENAMID
- DESMETHYL LOPERAMIDE
- Loperamide