GinsenosideRo
GinsenosideRo Basic information
- Product Name:
- GinsenosideRo
- Synonyms:
-
- (3beta)-28-(beta-D-Glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosiduronic acid
- Chikusetsusaponin 5
- ChikusetsusaponinV
- PolysciasaponinP3
- β-D-Glucopyranosiduronic acid, (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl2-O-β-D-glucopyranosyl-
- 28-(β-D-Glucopyranosyloxy)-28-oxo-5α-olean-12-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
- 28-(β-D-Glucopyranosyloxy)-28-oxoolean-12-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
- 3β-(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyloxy)oleana-12-ene-28-oic acid 28-β-D-glucopyranosyl ester
- CAS:
- 34367-04-9
- MF:
- C48H76O19
- MW:
- 957.11
- Product Categories:
-
- The group of Ginsenosides
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 34367-04-9.mol
GinsenosideRo Chemical Properties
- Boiling point:
- 1018.6±65.0 °C(Predicted)
- Density
- 1.14
- storage temp.
- Store at 2-8°C, protect from light
- solubility
- DMSO : 100 mg/mL (104.48 mM; Need ultrasonic)
- form
- powder
- pka
- 2.76±0.70(Predicted)
- color
- White
GinsenosideRo Usage And Synthesis
Description
Ginsenoside Ro is a non-steroid glycoside that has been found in plants of the genus Panax and has anti-inflammatory, antithrombotic, and antiviral biological activities. It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200 μM. Ginsenoside Ro dose-dependently inhibits human platelet aggregation induced by thrombin in vitro and thrombin-induced disseminated intravascular coagulation (DIC) in rats when administered at a dose of 100 mg/kg. It increases the 20-day survival of Sendai virus-infected mice when administered at a dose of 1 mg per day for three days prior to infection. Topical administration of ginsenoside Ro (0.2 mg per animal) also stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth.
Definition
ChEBI: A natural product found in Panax japonicus var. major.
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