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GinsenosideRo

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GinsenosideRo Basic information

Product Name:
GinsenosideRo
Synonyms:
  • (3beta)-28-(beta-D-Glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosiduronic acid
  • Chikusetsusaponin 5
  • ChikusetsusaponinV
  • PolysciasaponinP3
  • β-D-Glucopyranosiduronic acid, (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl2-O-β-D-glucopyranosyl-
  • 28-(β-D-Glucopyranosyloxy)-28-oxo-5α-olean-12-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
  • 28-(β-D-Glucopyranosyloxy)-28-oxoolean-12-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
  • 3β-(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyloxy)oleana-12-ene-28-oic acid 28-β-D-glucopyranosyl ester
CAS:
34367-04-9
MF:
C48H76O19
MW:
957.11
Product Categories:
  • The group of Ginsenosides
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
34367-04-9.mol
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GinsenosideRo Chemical Properties

Boiling point:
1018.6±65.0 °C(Predicted)
Density 
1.14
storage temp. 
Store at 2-8°C, protect from light
solubility 
DMSO : 100 mg/mL (104.48 mM; Need ultrasonic)
form 
powder
pka
2.76±0.70(Predicted)
color 
White
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Safety Information

HS Code 
29389090
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GinsenosideRo Usage And Synthesis

Description

Ginsenoside Ro is a non-steroid glycoside that has been found in plants of the genus Panax and has anti-inflammatory, antithrombotic, and antiviral biological activities. It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200 μM. Ginsenoside Ro dose-dependently inhibits human platelet aggregation induced by thrombin in vitro and thrombin-induced disseminated intravascular coagulation (DIC) in rats when administered at a dose of 100 mg/kg. It increases the 20-day survival of Sendai virus-infected mice when administered at a dose of 1 mg per day for three days prior to infection. Topical administration of ginsenoside Ro (0.2 mg per animal) also stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth.

Definition

ChEBI: A natural product found in Panax japonicus var. major.

GinsenosideRoSupplier

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