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Corynoxine

Basic information Safety Supplier Related

Corynoxine Basic information

Product Name:
Corynoxine
Synonyms:
  • (16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester
  • Corynoxine
  • Corynoxine A
  • Corynoxan-16-carboxylicacid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (16E)-
  • Corynoxine, 99.5%
  • Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'S,6'S,7'S,8'aS)-
  • (E)-methyl 2-((1'S,6'S,7'S,8a'S)-6'-ethyl-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate
CAS:
6877-32-3
MF:
C22H28N2O4
MW:
384.47
EINECS:
211-708-6
Mol File:
6877-32-3.mol
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Corynoxine Chemical Properties

Melting point:
166-168℃
Boiling point:
560.8±50.0 °C(Predicted)
Density 
1.23
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 100 mg/mL (260.10 mM);Water : < 0.1 mg/mL (insoluble)
pka
13.61±0.60(Predicted)
form 
Cryst.
color 
White to off-white
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Corynoxine Usage And Synthesis

Uses

Corynoxine is an indole alkaloid extracted from Uncaria plants, and have been shown to affect locomotor response in mice . Research points to a mediation of the central dopaminergic system.

Definition

ChEBI: A natural product found in Uncaria macrophylla.

target

Akt | mTOR | Autophagy

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