4-Methylpiperidine Chemical Properties

Melting point:

4-5 °C

Boiling point:

124 °C(lit.)

Density 

0.838 g/mL at 25 °C(lit.)

vapor pressure 

16 hPa (20 °C)

refractive index 

n20/D 1.446(lit.)

Flash point:

45 °F

storage temp. 

Flammables area

solubility 

Chloroform

form 

Liquid

pka

pK1:11.23(+1) (25°C,μ=0.5)

Specific Gravity

0.838

color 

Clear slightly yellow

PH

13 (100g/l, H2O, 20℃)

Water Solubility 

miscible

BRN 

1083

CAS DataBase Reference

626-58-4(CAS DataBase Reference)

NIST Chemistry Reference

Piperidine, 4-methyl-(626-58-4)

EPA Substance Registry System

Piperidine, 4-methyl- (626-58-4)

Safety Information

Hazard Codes 

F,Xi,T

Risk Statements 

11-36/37/38-36-20/21-10-61

Safety Statements 

16-26-36-45-36/37-53

RIDADR 

UN 1993 3/PG 2

WGK Germany 

3

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29333999

MSDS

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4-Methylpiperidine Usage And Synthesis

Chemical Properties

clear slightly yellow liquid

Uses

4-Methylpiperidine acts as a catalyst in the preparation of stilbene derivatives. It is used as an anti-corrosive compound for iron. It is also used in the synthesis of peptides to remove or deprotection of 9-fluorenylmethyloxycarbonyl (Fmoc) groups.

Uses

4-Methylpiperidine is used as a catalyst in the synthesis of stilbene derivatives as anti-malarial agents. It also serves as an anti-corrosive compound for iron.

Purification Methods

Purify it via the hydrochloride (m 189o). It is freed from 3-methylpyridine by zone melting. The hydrobromide has m 173o(from butanone/*C6H6). [Beilstein 20 III/IV 1511, 20/4 V 116.]

4-Methylpiperidine(626-58-4)Related Product Information

• 4,4'-Bipiperidine dihydrochloride
• 4-(Aminomethyl)piperidine
• STRYCHNINE
• 4-Phenylpiperidine
• 1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE
• Reserpine
• 3-ETHYL-3-METHYLGLUTARIMIDE
• Ethyl 4-piperidinecarboxylate
• 4-Benzylpiperidine
• 4-(4-Chlorophenyl)piperidin-4-ol
• 4-HYDROXY-4-PHENYLPIPERIDINE
• Yohimbine
• 10,11-Dimethoxystrychnine
• 4,4'-Trimethylenebis(1-methylpiperidine)
• 3,3-DIMETHYLGLUTARIMIDE
• RESCINNAMINE
• 4-Piperidineethanol
• 4-Methylpiperidine