cyprodime
cyprodime Basic information
- Product Name:
- cyprodime
- Synonyms:
-
- 17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one
- 17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride
- Cyprodime hydrochloride
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,14-dimethoxy-
- CAS:
- 118111-54-9
- MF:
- C22H29NO3
- MW:
- 355.47
- Mol File:
- 118111-54-9.mol
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cyprodime Chemical Properties
- Melting point:
- 155-159 °C(Solv: methanol (67-56-1))
- Boiling point:
- 504.0±50.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- form
- Powder
- pka
- 7.42±0.40(Predicted)
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cyprodime Usage And Synthesis
Uses
Selective μ-opioid receptor antagonist. Reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease.
Biological Activity
Selective μ -opioid receptor antagonist (K i values are 5.4, 244.6 and 2187 nM for μ -, δ - and κ -opioid receptors respectively). Reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease.